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 Allergy Advisor Digest - December 2014
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Read Allergic bronchopulmonary aspergillosis.
Read Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence.
Read Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes.
Read The natural history of peanut sensitization and allergy in a birth cohort.
Read Hay fever as a Christmas gift.
Read Skin tests and in vitro allergy tests have a poor diagnostic value for benign skin rashes due to beta-lactams in children.
Read Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies.
Read Measurement of aeroallergens from furnace filters.
Read Relationships between T-cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1.
Read Standardized food challenges are subject to variability in interpretation of clinical symptoms.
Read Allergic contact eczema caused by exotic wood material in sauna interior decoration.
Read Natural rubber gloves might not protect against skin penetration of methylisothiazolinone.

Abstracts shared in December 2014 Advisor Digest Newsletter

Read Is there a risk using hypoallergenic cosmetic pediatric products in the United States?
Read Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy.
Read Native and denatured egg white protein IgE tests discriminate hen's egg allergic from egg tolerant children.
Read Urticarial syndrome related to syphilis (Treponema) infection.
Read Contact urticaria on eczematous skin by kiwifruit allergy.
Read Peanut allergy is common amongst hazelnut sensitized subjects but is not primarily the result of IgE cross-reactivity.
Read Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Read Clinical monosensitivity to cod and perch with specific IgE to enolase and aldolase.
Read Anaphylaxis induced by gelatin-contained gel capsule cold medicine.
Read Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement.

Allergy and Intolerance Abstracts
Allergic bronchopulmonary aspergillosis.
There remains a lack of agreement on diagnostic criteria and approaches to treatment of patients with allergic bronchopulmonary aspergillosis (ABPA). The results of a survey of American Academy of Allergy, Asthma, & Immunology members regarding these 2 issues are presented and compared for concordance with published recommendations. The literature was reviewed for pertinent reports, and an electronic survey was conducted of American Academy of Allergy, Asthma, & Immunology members and fellows regarding diagnostic criteria, numbers of patients evaluated for ABPA, and treatment approaches. From 508 respondents to the survey sent to 5155 US physicians in the American Academy of Allergy, Asthma, & Immunology database of members and fellows, 245 health professionals (48%) had treated at least 1 patient with ABPA in the previous year. For the diagnosis of ABPA, there was a difference in the threshold concentration of total serum IgE because 44.9% used >/=417 kU/L, whereas 42.0% used >/=1000 kU/L. Analysis of these findings suggests that ABPA might be underdiagnosed. With regard to pharmacotherapy, oral steroids were recommended for 97.1% of patients and oral steroids plus inhaled corticosteroids plus antifungal agent were used with 41.2% of patients. The armamentarium for treatment of ABPA includes oral corticosteroids as the initial treatment with inhaled corticosteroids used for management of persistent asthma. Azoles remain adjunctive. Published experience with omalizumab has been limited

Allergic bronchopulmonary aspergillosis.  
Greenberger PA, Bush RK, Demain JG, Luong A, Slavin RG, Knutsen AP.
J Allergy Clin Immunol Pract 2014 Nov;2(6):703-708

Click to view abstract

Index
Allergy and Intolerance Abstracts
Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence.
The authors sought to investigate the association between IgE reactivity to the pathogenesis-related class 10 (PR-10) protein family and allergic rhinitis to birch pollen (ARbp) from early childhood up to age 16 years. Questionnaire data and sera obtained at 4, 8, and 16 years of age from the Barn/Children Allergi/Allergy Milieu Stockholm Epidemiologic (BAMSE) study birth cohort were used. Sera from 764 children were analyzed for IgE reactivity to 9 PR-10 allergen proteins at the 3 time points by using an allergen chip based on ISAC technology. IgE reactivity to Bet v 1 was found in 12%, 17%, and 25% of children at 4, 8, and 16 years of age. IgE reactivity of PR-10 proteins showed a hierarchic intrarelationship: Bet v 1 > Mal d 1 > Cor a 1.04 > Ara h 8 > Pru p 1 > Aln g 1 > Api g 1 > Act d 8 > Gly m 4. There was an increased risk of incidence and persistence of ARbp up to age 16 years with increasing levels of Bet v 1-specific IgE or increasing numbers of IgE-reactive PR-10 proteins at 4 years. Children with severe ARbp at age 16 years had higher levels of Bet v 1-specific IgE at age 4 years compared with children with mild symptoms. The authors conclude that ARbp at age 16 years can be predicted by analysis of IgE reactivity to PR-10 proteins in early childhood.

Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence.  
Westman M, Lupinek C, Bousquet J, Andersson N, Pahr S, Baar A, Bergstrom A, Holmstrom M, Stjarne P, Lodrup Carlsen KC, Carlsen K, Anto JM, Valenta R, van HM, Wickman M.
J Allergy Clin Immunol 2014 Dec 18;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes.
This study investigated the effect of proline hydroxylation on IgE binding and the relative contributions of linear and conformational epitopes to Ara h 2 allergenicity. The authors report that sensitization toward linear and conformational epitopes of Ara h 2 is variable among patients with peanut allergy. Optimal IgE binding to linear epitopes of Ara h 2 requires posttranslational hydroxylation of proline residues. The absence of hydroxyprolines could then affect the accuracy of component-resolved diagnostics by using rAra h 2.

Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes.  
Bernard H, Guillon B, Drumare MF, Paty E, Dreskin SC, Wal JM, del-Patient K, Hazebrouck S.
J Allergy Clin Immunol 2014 Dec 4;

Click to view abstract

Index
Allergy and Intolerance Abstracts
The natural history of peanut sensitization and allergy in a birth cohort.
The natural history of peanut-induced allergic sensitization (PAS) and clinical peanut allergy (PA) is reported from the Isle of Wight birth cohort (n = 1456). PAS increased gradually in the first decade of life but showed a steeper increase from 10 to 18 years of age. At age 4 years, 13 (1.3%) of 976 children were sensitized to peanut. This increased to 19 (1.8%) of 1034 children at age 10 years, with a further increase to 54 (6.4%) of 851 children at age 18 years. There was minimal change in the overall prevalence of PA beyond early childhood, and it remained around 0.6%. Remission of PA was seen in 1 (17%) of 6 children between ages 4 and 10 years and 1 (25%) of 4 children from age 10 to 18 years. (The authors point out that the numbers with PA in the study were small, and therefore these findings should be interpreted with caution.)

The natural history of peanut sensitization and allergy in a birth cohort.  
Arshad SH, Venter C, Roberts G, Dean T, Kurukulaaratchy R.
J Allergy Clin Immunol 2014 Dec;134(6):1462-1463

Index
Allergy and Intolerance Abstracts
Hay fever as a Christmas gift.
A changing pattern of allergic sensitization to pollens is reported from Switzerland, of allergic symptoms and serologic findings among 15-year-olds attending school in Grabs, a village in eastern Switzerland, from 1983 through 2007. IgE antibodies against the main allergen of alder trees (Aln g 1), which were not detected in any child in 1986, were found in 10.9% of unselected healthy schoolchildren in 2006. This increased prevalence of sensitization was not seen with pollen of other trees, such as birch, hazel, ash, or plane. Among the 12 former students who were tested at the ages of 15 and 39 years, 3 (25%) showed newly detectable IgE antibodies to alder pollen in 2010. Although none of the schoolchildren reported having had allergic symptoms in December from 1983 through 1986, 6 students had such symptoms in 2006; all were sensitized to alder pollen. Just over a decade ago, 96 hybrid trees with high winter resistance (Alnus x spaethii: A. japonica x A. subcordata) were planted along a main boulevard in Buchs, where children walk or ride the bus on their way to school in Grabs. This leads to almost daily pollen exposure during the flowering season, which for alders in this region of Switzerland is in December.

Hay fever as a Christmas gift.  
Gassner M, Gehrig R, Schmid-Grendelmeier P.
N Engl J Med 2013 Jan 24;368(4):393-394

Index
Allergy and Intolerance Abstracts
Skin tests and in vitro allergy tests have a poor diagnostic value for benign skin rashes due to beta-lactams in children.
Skin rashes are frequent in children treated by beta-lactams (BL), with an estimated incidence ranging between 1% and 5%. In clinical practice, most of these children are labeled as 'penicillin allergic' without appropriate testing, mostly due to fear of life-threatening reactions. However, an allergic reaction can be demonstrated by an oral provocation test (OPT) in less than 10% of the patients developing a rash while treated by BL.

Skin tests and in vitro allergy tests have a poor diagnostic value for benign skin rashes due to beta-lactams in children.  
Caubet JC, Frossard C, Fellay B, Eigenmann PA.
Pediatr Allergy Immunol 2014 Dec 3;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies.
"Probability curves predicting oral food challenge test (OFC) results based on specific-IgE levels are widely used to prevent serious allergic reactions. Although several confounding factors are known to affect probability curves, the main factors that affect OFC outcomes are currently unclear. We hypothesized that an increased total IgE level would reduce allergic reactivity. Medical records of 337 and 266 patients who underwent OFCs for 3.5 g boiled hen's egg white and 3.1 mL raw cow's milk, respectively, were examined retrospectively. We subdivided the patients into three groups based on total IgE levels and age by percentile (<25th, 25-75th, and >75th percentiles), and logistic regression analyses were performed on each group. Patients with higher total IgE levels were significantly less responsive. In addition, age did not significantly affect the OFC results. Therefore, total IgE levels should be taken into account when predicting OFC results based on food-specific IgE levels."

Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies.  
Horimukai K, Hayashi K, Tsumura Y, Nomura I, Narita M, Ohya Y, Saito H, Matsumoto K.
Allergy 2014 Dec 15;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Measurement of aeroallergens from furnace filters.
The objective of this study was to measure allergen levels of dust taken from high-efficiency furnace filters in Midwestern homes. Sixty filters were recovered from 56 homes after an average 135 days in situ. Allergens from 5 common aeroallergen species and antigenic material from 4 common fungal taxa can be measured in dust taken from high-efficiency furnace filters. Viable spore counts ranged to 4.8 x 107 per gram of dust. Mean fungal antigenic material ranged to 42 mug per gram for Cladosporium species. Mean aeroallergen material ranged to 7 mug per gram for Fel d1. Aeroallergen measurements were above the level of detection in 100% of houses for Fel d1 and 89% of houses for Bla g2. Levels of Fel d1 and Can f1 were strongly positively correlated.

Measurement of aeroallergens from furnace filters.  
Barnes CS, Allenbrand R, Mohammed M, Gard L, Pacheco F, Kennedy K, Portnoy JM, Ciaccio C.
Ann Allergy Asthma Immunol 2014 Nov 18;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Relationships between T-cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1.
Anisakiasis is a global disease caused by the consumption of raw or lightly cooked fish parasitized with third-stage Anisakis larvae. Anisakis simplex allergens may cause severe allergic reactions including angio-oedema, urticaria and anaphylaxis. Approximately 80% of allergic patients have allergen-specific IgE against Ani s 1, and the diagnostic value of testing for antibodies to Ani s 1 has been extensively demonstrated. However, no previous studies have investigated the molecular aspects of the allergic response to Ani s 1. Several T-cell epitopes of Ani s 1 were identified, of which Ani s 1145-156 , Ani s 1151-162 and Ani s 1163-171 located at the C-terminal end of the protein were the most relevant. IgE and IgG4 recognized largely the same peptides, including Ani s 122-41 , Ani s 125-44 , Ani s 127-47 , Ani s 137-56 and Ani s 194-113 .

Relationships between T-cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1.  
Alonso MG, Caballero ML, Umpierrez A, Lluch-Bernal M, Knaute T, Rodriguez-Perez R.
Clin Exp Allergy 2014 Dec 11;

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Index
Allergy and Intolerance Abstracts
Standardized food challenges are subject to variability in interpretation of clinical symptoms.
This study aimed to assess inter- and intra-observer variability in outcomes of routinely performed peanut challenges in children. All complete food challenge score sheets of double blind placebo controlled peanut challenges performed in 2008-2010 in an academic hospital were included. Score sheets were reassessed independently by three clinical experts including double reassessment in a subset of score sheets. Inter- and intra-observer variability was evaluated using kappa statistics. The authors demonstrate that, despite strict adherence to guidelines, there was a considerable amount of variability in reassessment of symptoms recorded on food challenges sheets between and within well trained clinicians, especially when subjective symptoms occur.

Standardized food challenges are subject to variability in interpretation of clinical symptoms.  
van Erp FC, Knulst AC, Meijer Y, Gabriele C, van der Ent CK.
Clin Transl Allergy 2014;4(1):43

Click to view abstract

Index
Allergy and Intolerance Abstracts
Allergic contact eczema caused by exotic wood material in sauna interior decoration.
A 45-year-old female teacher with severe and treatment-resistant dermatitis. Dermatitis first appeared in her right elbow and upper arm. Over the next few weeks, the dermatitis spread to her back and left upper arm. The cause was found to be the interior material of a nrewly renovated sauna made from unvarnished western red cedar. Patch testing for western red cedar sawdust gave a firmly positive (++) reaction.

Allergic contact eczema caused by exotic wood material in sauna interior decoration.  
Kubin ME, Riekki R.
Contact Dermatitis 2014 Apr;70(4):255-256

Index
Allergy and Intolerance Abstracts
Natural rubber gloves might not protect against skin penetration of methylisothiazolinone.
Natural rubber gloves might not protect against skin penetration of methylisothiazolinone. A 55-year-old female nurse presented with chronic eczematous lesions on both hands of approximately 20 years duration, but with an acute worsening. Patch tests had been performed shortly after the lesions had started to develop, and revealed contact allergy to the mixture of methylchloro and methylisothiazolinone (MCI/MI). The patient referred to intolerance when her skin came into contact with potatoes, cucumbers, and tomatoes. The study demonstrates that MI can penetrate natural rubber gloves, which, in this case, explained the severity and chronicity of the patientÂ’s dermatitis when daily and repeatedly handling the Mi containing detergent.

Natural rubber gloves might not protect against skin penetration of methylisothiazolinone.  
Espasandin-Arias M, Goossens A.
Contact Dermatitis 2014 Apr;70(4):249-251

Index

Allergen-, Food allergy-, Intolerance-related articles

Developing therapies for peanut allergy.  
Bublin M, Breiteneder H.
Int Arch Allergy Immunol 2014 Dec 20;165(3):179-194
Click to view abstract

Dusty air pollution is associated with an increased risk of allergic diseases in southwestern part of Iran.  
Gheybi MK, Movahed AM, Dehdari R, Amiri S, Khazaei HA, Gooya M, Dehbashi F, Fatemi A, Sovid N, Hajiani G, Tahmasebi R, Dobaraderan S, Assadi M, Farrokhi S.
Iran J Allergy Asthma Immunol 2014 Dec;13(6):396-403
Click to view abstract

Aspirin or other nonsteroidal inflammatory agent exacerbated asthma.  
Ledford DK, Wenzel SE, Lockey RF.
J Allergy Clin Immunol Pract 2014 Nov;2(6):653-657
Click to view abstract

Drug-induced anaphylaxis in children: Nonsteroidal anti-inflammatory drugs and drug provocation test.  
Ensina LF, de Lacerda AE, de Andrade DM, Machado L, Camelo-Nunes I, Sole D.
J Allergy Clin Immunol Pract 2014 Nov;2(6):825

A case report of allergy to exenatide.  
Perez E, Martinez-Tadeo J, Callero A, Hernandez G, Rodriguez-Plata E, Garcia-Robaina JC.
J Allergy Clin Immunol Pract 2014 Nov;2(6):822-823

Cross-reactivity between carbapenems: Two case reports.  
Noguerado-Mellado B, Pinto FC, Pineda-Pineda R, Martinez LP, varez-Perea A, De Barrio FM.
J Allergy Clin Immunol Pract 2014 Nov;2(6):816-817

Percutaneous and intradermal allergy skin test utilization in the United States 2012 Medicare population.  
Nickels AS, Li JT, Volcheck G.
J Allergy Clin Immunol Pract 2014 Nov;2(6):807-809

Iodinated contrast media-induced acute generalized exanthematous pustulosis confirmed by delayed skin tests.  
Grandvuillemin A, Ripert C, Sgro C, Collet E.
J Allergy Clin Immunol Pract 2014 Nov;2(6):805-806

Is skin testing reliable for confirming sensitization to seminal fluid proteins?  
Tal Y, Bernstein JA, Lorberbaum M, Ghosh D, Dranitzki Z.
J Allergy Clin Immunol Pract 2014 Nov;2(6):798-799

Allergic bronchopulmonary aspergillosis.  
Greenberger PA, Bush RK, Demain JG, Luong A, Slavin RG, Knutsen AP.
J Allergy Clin Immunol Pract 2014 Nov;2(6):703-708
Click to view abstract

Transmission of allergen-specific IgG and IgE from maternal blood into breast milk visualized with microarray technology.  
Hochwallner H, Alm J, Lupinek C, Johansson C, Mie A, Scheynius A, Valenta R.
J Allergy Clin Immunol 2014 Nov;134(5):1213-1215

Comparison of indoor allergen levels in urban and suburban Detroit.  
Veras L, Wegienka G, Havstad S, Kim H, Johnson C, Ownby D, Zoratti E.
J Allergy Clin Immunol 2014 Nov;134(5):1189-1190

Fatal anaphylaxis in the United States, 1999-2010: Temporal patterns and demographic associations.  
Jerschow E, Lin RY, Scaperotti MM, McGinn AP.
J Allergy Clin Immunol 2014 Dec;134(6):1318-1328
Click to view abstract

Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice.  
Moghaddam AE, Hillson WR, Noti M, Gartlan KH, Johnson S, Thomas B, Artis D, Sattentau QJ.
J Allergy Clin Immunol 2014 Dec;134(6):1453-1456

Arginine kinase Pen m 2 as an important shrimp allergen recognized by TH2 cells.  
Renand A, Newbrough S, Wambre E, DeLong JH, Robinson D, Kwok WW.
J Allergy Clin Immunol 2014 Dec;134(6):1456-1459

Immune factors in breast milk related to infant milk allergy are independent of maternal atopy.  
Jarvinen KM, Suarez-Farinas M, Savilahti E, Sampson HA, Berin MC.
J Allergy Clin Immunol 2014 Dec 19;

Staphylococcus aureus colonization is associated with wheeze and asthma among US children and young adults.  
Davis MF, Peng RD, McCormack MC, Matsui EC.
J Allergy Clin Immunol 2014 Dec 20;

Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence.  
Westman M, Lupinek C, Bousquet J, Andersson N, Pahr S, Baar A, Bergstrom A, Holmstrom M, Stjarne P, Lodrup Carlsen KC, Carlsen K, Anto JM, Valenta R, van HM, Wickman M.
J Allergy Clin Immunol 2014 Dec 18;
Click to view abstract

Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes.  
Bernard H, Guillon B, Drumare MF, Paty E, Dreskin SC, Wal JM, del-Patient K, Hazebrouck S.
J Allergy Clin Immunol 2014 Dec 4;
Click to view abstract

Understanding food allergen thresholds requires careful analysis of the available clinical data.  
Taylor SL, Houben GF, Baumert JL, Crevel RR, Allen KJ, Dubois AE, Knulst AC, Remington BC, Kruizinga AG, Blom WM, Brooke-Taylor S.
J Allergy Clin Immunol 2014 Nov 22;

Symptom dynamics during repeated serial allergen challenge chamber exposures to house dust mite.  
Jacobs RL, Andrews CP, Ramirez DA, Rather CG, Harper N, Jimenez F, Martinez H, Manoharan M, Carrillo A, Gerardi M, Esch RE, He W, Ahuja SK.
J Allergy Clin Immunol 2014 Nov 11;

Is there a risk using hypoallergenic cosmetic pediatric products in the United States?  
Hamann CR, Bernard S, Hamann D, Hansen R, Thyssen JP.
J Allergy Clin Immunol 2014 Nov 7;

'Default' versus 'pre-atopic' IgG responses to foodborne and airborne pathogenesis-related group 10 protein molecules in birch-sensitized and nonatopic children.  
Hofmaier S, Hatzler L, Rohrbach A, Panetta V, Hakimeh D, Bauer CP, Hoffman U, Forster J, Zepp F, Schuster A, Stock P, Wahn U, Keil T, Lau S, Matricardi PM.
J Allergy Clin Immunol 2014 Nov 22;
Click to view abstract

Hypersensitivity reactions to racemic calcium folinate (leucovorin) during FOLFOX and FOLFIRI chemotherapy administrations.  
Urena-Tavera A, Zamora-Verduga M, Madrigal-Burgaleta R, ngel-Pereira D, Berges-Gimeno MP, varez-Cuesta E.
J Allergy Clin Immunol 2014 Nov 7;

Respiratory allergy caused by house dust mites: What do we really know?  
Calderon MA, Linneberg A, Kleine-Tebbe J, De BF, Hernandez Fernandez de RD, Virchow JC, Demoly P.
J Allergy Clin Immunol 2014 Nov 22;
Click to view abstract

When are serum specific IgE levels positive?  
Scala G, Miceli SS.
J Allergy Clin Immunol 2014 Nov 20;

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy.  
Brough HA, Liu AH, Sicherer S, Makinson K, Douiri A, Brown SJ, Stephens AC, Irwin McLean WH, Turcanu V, Wood RA, Jones SM, Burks W, Dawson P, Stablein D, Sampson H, Lack G.
J Allergy Clin Immunol 2014 Nov 18;
Click to view abstract

The natural history of peanut sensitization and allergy in a birth cohort.  
Arshad SH, Venter C, Roberts G, Dean T, Kurukulaaratchy R.
J Allergy Clin Immunol 2014 Dec;134(6):1462-1463

Food allergy in patients with primary immunodeficiency diseases: Prevalence within the US Immunodeficiency Network (USIDNET).  
Tuano KS, Orange JS, Sullivan K, Cunningham-Rundles C, Bonilla FA, Davis CM.
J Allergy Clin Immunol 2014 Nov 25;

Bedroom air quality and vacuuming frequency are associated with repeat child asthma hospital admissions.  
Vicendese D, Dharmage SC, Tang ML, Olenko A, Allen KJ, Abramson MJ, Erbas B.
J Asthma 2014 Dec 24;1-17
Click to view abstract

Perennial aeroallergens sensitisation and risk of asthma in African children and adolescents: a case-control study.  
Pefura-Yone EW, Mbele-Onana CL, Balkissou AD, Kenmegne-Noumsi EC, Boulleys-Nana JR, Kolontchang-Yomi BL, Theubo-Kamgang BJ, Ndjeutcheu-Moualeu PI, Ebouki ER, Kengne AP.
J Asthma 2014 Dec 26;1-5
Click to view abstract

Hay fever as a Christmas gift.  
Gassner M, Gehrig R, Schmid-Grendelmeier P.
N Engl J Med 2013 Jan 24;368(4):393-394

Skin tests and in vitro allergy tests have a poor diagnostic value for benign skin rashes due to beta-lactams in children.  
Caubet JC, Frossard C, Fellay B, Eigenmann PA.
Pediatr Allergy Immunol 2014 Dec 3;
Click to view abstract

Native and denatured egg white protein IgE tests discriminate hen's egg allergic from egg tolerant children.  
Benhamou Senouf AH, Borres MP, Eigenmann PA.
Pediatr Allergy Immunol 2014 Dec 2;
Click to view abstract

Adverse reaction to not iodinated contrast. [Spanish]  
Palma-Gomez S, Gonzalez-Diaz SN, rias-Cruz A, ias-Weinmann A, maro-Vivian LE, Perez-Vanzzini R, Gutierrez-Mujica JJ, Yong-Rodriguez A.
Rev Alerg Mex 2014 Oct;61(4):368-371
Click to view abstract

Urticarial syndrome related to Treponema infection. [Spanish]  
Bello L, Mimessi G, Gomez M.
Rev Alerg Mex 2014 Oct;61(4):363-367
Click to view abstract

Frequency of sensitization to pollens of the subclass Rosidae in patients with respiratory allergy. [Spanish]  
Bedolla-Barajas M, Valdez-Lopez F, rceo-Barba J, Bedolla-Pulido TR, Hernandez-Colin D, Morales-Romero J.
Rev Alerg Mex 2014 Oct;61(4):327-335
Click to view abstract

Food allergy diagnosis in patients with elimination diet history. Preliminary report. [Spanish]  
Navarrete-Rodriguez EM, Del Rio-Navarro BE, Pozo-Beltran CF, Garcia-Fajardo DE, Saucedo-Ramirez OJ, Castelan-Chavez EE.
Rev Alerg Mex 2014 Oct;61(4):298-304
Click to view abstract

Frequency of allergy to cow's milk proteins and its association to other allergic diseases in patients of Hospital Infantil de Mexico Federico Gomez. [Spanish]  
Robles-Vargas MT, Sienra-Monge JJ, Del Rio-Navarro BE, Reyes-Lopez A, Del Rio-Chivardi J.
Rev Alerg Mex 2014 Oct;61(4):288-297
Click to view abstract

Dust mites as occupational allergens in two bakeries of La Habana, Cuba. [Spanish]  
Fernandez-Duro BI, varez-Castello M, Mateo-Morejon M, Luis-Rodriguez B, Labrada-Rosado A.
Rev Alerg Mex 2014 Oct;61(4):281-287
Click to view abstract

Contact urticaria on eczematous skin by kiwifruit allergy. In vivo component-resolved diagnosis.  
Miceli SS, Fantacci C, Sani I.
Allergol Immunopathol (Madr ) 2014 Nov 11;
Click to view abstract

Respiratory allergy in immigrants to a highly industrialised area in Italy according to area of origin and time period.  
Minetti S, Raffetti E, Lodi-Rizzini F, Facchetti S, Schlanser E, Colombo E, Cinquini M, Donato F, Tosoni C.
Allergol Immunopathol (Madr ) 2014 Nov 8;
Click to view abstract

When should the skin prick tests not be performed?  
Liccardi G, Steinhilber G, Meriggi A, Piccolo A, Salzillo GF, Manzi V, Salzillo A.
Allergol Immunopathol (Madr ) 2014 Nov 8;

Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies.  
Horimukai K, Hayashi K, Tsumura Y, Nomura I, Narita M, Ohya Y, Saito H, Matsumoto K.
Allergy 2014 Dec 15;
Click to view abstract

The influence of childhood traffic related air pollution exposure on asthma, allergy and sensitization: a systematic review and a meta-analysis of birth cohort studies.  
Bowatte G, Lodge C, Lowe AJ, Erbas B, Perret J, Abramson MJ, Matheson M, Dharmage S.
Allergy 2014 Dec 14;
Click to view abstract

Environmental Tobacco Smoke Exposure, Urine CC-16 Levels, and Asthma Outcomes among Chinese Children.  
Ma YN, Qian Z, Wang J, Rodemich E, Lee YL, Lv XF, Liu YQ, Zhao Y, Huang MM, Liu Y, Sun J, He QC, Dong GH.
Allergy 2014 Dec 12;
Click to view abstract

Peanut allergy is common amongst hazelnut sensitized subjects but is not primarily the result of IgE cross-reactivity.  
Masthoff LJ, van HE, Mattsson L, Lidholm J, Andersson K, Zuidmeer-Jongejan L, Versteeg SA, Bruijnzeel-Koomen CA, Knulst AC, Pasmans SG, van RR.
Allergy 2014 Dec 5;
Click to view abstract

Detection of nickel and palladium contact hypersensitivity by a flow cytometric lymphocyte proliferation test.  
Spoerri I, Scherer K, Michel S, Link S, Bircher AJ, Heijnen IA.
Allergy 2014 Dec 2;
Click to view abstract

Allergen-specific basophil reactivity exhibits daily variations in seasonal allergic rhinitis.  
Ando N, Nakamura Y, Ishimaru K, Ogawa H, Okumura K, Shimada S, Nakao A.
Allergy 2014 Dec 2;
Click to view abstract

Basophil responses to peanut allergens.  
Moneret-Vautrin DA, Mayorga L.
Allergy 2014 Dec;69(12):1701-1702

Predictors of anaphylaxis in Korean adults.  
Park HW.
Allergy Asthma Immunol Res 2015 Jan;7(1):1-2

Development of Aspergillus protease with ovalbumin-induced allergic chronic rhinosinusitis model in the mouse.  
Kim JH, Yi JS, Gong CH, Jang YJ.
Am J Rhinol Allergy 2014 Nov;28(6):465-470
Click to view abstract

Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.  
Guillen D, Fiandor A, Del P, Pedrosa M, Phillips-Angles E, Caballero T, Quirce S.
Ann Allergy Asthma Immunol 2014 Oct 9;

Correlation of clinical monosensitivity to cod with specific IgE to enolase and aldolase.  
Kuehn A, Fischer J, Hilger C, Sparla C, Biedermann T, Hentges F.
Ann Allergy Asthma Immunol 2014 Oct 7;

Traffic pollution is associated with early childhood aeroallergen sensitization.  
Codispoti CD, LeMasters GK, Levin L, Reponen T, Ryan PH, Biagini Myers JM, Villareal M, Burkle J, Evans S, Lockey JE, Khurana Hershey GK, Bernstein DI.
Ann Allergy Asthma Immunol 2014 Dec 10;
Click to view abstract

Differences in empowerment and quality of life among parents of children with food allergy.  
Warren CM, Gupta RS, Sohn MW, Oh EH, Lal N, Garfield CF, Caruso D, Wang X, Pongracic JA.
Ann Allergy Asthma Immunol 2014 Dec 6;
Click to view abstract

Allergen of the month-black wattle.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Dec;113(6):A13

Positive house dust mite skin test in a nonatopic patient with scabies.  
Bajoghli AA, Bajoghli M, Adler S.
Ann Allergy Asthma Immunol 2014 Dec;113(6):667

Anaphylaxis due to topical pramoxine.  
Kim SJ, Goldberg BJ.
Ann Allergy Asthma Immunol 2015 Jan;114(1):72-73

Measurement of aeroallergens from furnace filters.  
Barnes CS, Allenbrand R, Mohammed M, Gard L, Pacheco F, Kennedy K, Portnoy JM, Ciaccio C.
Ann Allergy Asthma Immunol 2014 Nov 18;
Click to view abstract

Different sensitization to storage mites depending on the co-exposure to house dust mites.  
Morales M, Iraola V, Leonor JR, Bartra J, Rodriguez F, Boquete M, Huertas AJ, Paniagua MJ, Pinto H, Carnes J.
Ann Allergy Asthma Immunol 2015 Jan;114(1):36-42
Click to view abstract

Allergen of the month-chinese elm.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Nov;113(5):A15

Aspirin exacerbated respiratory disease: the search for a biomarker.  
Cahill KN, Laidlaw TM.
Ann Allergy Asthma Immunol 2014 Nov;113(5):500-501

A case of anaphylaxis induced by gelatin-contained gel capsule cold medicine. [Japanese]  
Tanaka M, Inomata N, Matsuura M, Ishida S, Suzuki A, Sohara M, Aihara M.
Arerugi 2014 Nov;63(9):1258-1264
Click to view abstract

Japanese Society of Allergology Task Force report on standardization of house dust mite allergen vaccines. [Japanese]  
Takai T, Okamoto Y, Okubo K, Nagata M, Sakaguchi M, Fukutomi Y, Saito A, Yasueda H, Masuyama K.
Arerugi 2014 Nov;63(9):1229-1240
Click to view abstract

Development of the studies on environmental chemicals and allergy. [Japanese]  
Honda A, Koike E, Yanagisawa R, Inoue K, Takano H.
Arerugi 2014 Nov;63(9):1205-1214

Food allergens affect the intestinal tight junction permeability in inducing intestinal food allergy in rats.  
Chen T, Liu X, Ma L, He W, Li W, Cao Y, Liu Z.
Asian Pac J Allergy Immunol 2014 Dec;32(4):345-353
Click to view abstract

Incidence of food anaphylaxis in people with food allergy: a systematic review and meta-analysis.  
Umasunthar T, Leonardi-Bee J, Turner PJ, Hodes M, Gore C, Warner JO, Boyle RJ.
Clin Exp Allergy 2014 Dec 11;
Click to view abstract

A food allergy syndrome by any other name?  
Turner PJ, Campbell DE.
Clin Exp Allergy 2014 Dec;44(12):1458-1460

Relationships between T-cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1.  
Alonso MG, Caballero ML, Umpierrez A, Lluch-Bernal M, Knaute T, Rodriguez-Perez R.
Clin Exp Allergy 2014 Dec 11;
Click to view abstract

Epidemiology of anaphylaxis.  
Tejedor Alonso MA, Moro MM, Mugica Garcia MV.
Clin Exp Allergy 2014 Dec 15;
Click to view abstract

Standardized food challenges are subject to variability in interpretation of clinical symptoms.  
van Erp FC, Knulst AC, Meijer Y, Gabriele C, van der Ent CK.
Clin Transl Allergy 2014;4(1):43
Click to view abstract

Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement.  
De Marchi S, Cecchin E, De Marchi SU.
Contact Dermatitis 2014 Feb;70(2):123-125

Allergic contact eczema caused by exotic wood material in sauna interior decoration.  
Kubin ME, Riekki R.
Contact Dermatitis 2014 Apr;70(4):255-256

Natural rubber gloves might not protect against skin penetration of methylisothiazolinone.  
Espasandin-Arias M, Goossens A.
Contact Dermatitis 2014 Apr;70(4):249-251


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