Allergy and Intolerance Information
Allergy and Intolerance Information
Allergy and Intolerance InformationAllergy AdvisorAllergy Resources International
Allergy and Intolerance InformationAllAllergy.net
Allergy and Intolerance Information
Allergy and Intolerance Information
Allergy and Intolerance Information
Index Allergens and Substances List Allergy Advisor Digest Contents of Journals Allergen and Substance Search
Phadia Allergy, Asthma and intolerance information
 Allergy Advisor Digest - August 2017
Editor: Dr. Harris A. Steinman

Journals List | Journals Captured this Month | ALL Articles captured this Month

Previous Issues | All
August 2015   September 2015   October 2015   November 2015   December 2015   January 2016   February 2016   March 2016   April 2016   May 2016   June 2016   July 2016   August 2016   September 2016   October 2016   November 2016   December 2016   January 2017   February 2017   March 2017   April 2017   May 2017   June 2017   July 2017   August 2017   September 2017  

This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
Want to subscribe to our reminder service? 

Snippets NOT posted in the August 2017 Advisor Digest Newsletter

Read Evolution of the IgE and IgG repertoire to a comprehensive array of allergen molecules in the first decade of life.
Read Characteristics of severe asthma with fungal sensitization.
Read Food allergen extracts to diagnose food-induced allergic diseases: How they are made.
Read Solenopsis geminata (tropical fire ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.
Read The role of environmental exposure to peanut in the development of clinical allergy to peanut.
Read Update on Quinolone Allergy.
Read Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder?
Read The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.
Read Risk of allergic reactions to recurrent intravenous penicillin administration in penicillin skin test negative patients.

Snippets posted in the August 2017 Advisor Digest Newsletter

Read Poor sleep is highly associated with house dust mite allergic rhinitis in adults and children.
Read Hydrolysed ovalbumin offers more effective preventive and therapeutic protection against egg allergy than the intact protein.
Read Relevance of lipophilic allergens in food allergy diagnosis.
Read Diagnosis of allergy to mammals and fish: Cross-reactive vs. specific markers.
Read Do advanced glycation end-products cause food allergy?
Read Molecular Recognition Profiles and Clinical Patterns of PR-10 Sensitization in a Birch-Free Mediterranean Area.

Allergy and Intolerance Abstracts
Evolution of the IgE and IgG repertoire to a comprehensive array of allergen molecules in the first decade of life.
The objective of this study was to investigate the evolution of IgG and IgE responses to a broad panel of allergenic molecules from birth to age 10yrs. The sera collected between birth and age 10yrs from participants in the German Multicentre Allergy Study, a birth cohort born in 1990 were assessed. The evolution of IgG and IgE responses throughout childhood differs widely at population level. IgG responses are mostly directed to animal food allergens while IgE responses are dominated by airborne allergens. However, a strong IgG response almost invariably precedes or accompanies the appearance of IgE to the same molecule in specifically sensitized subjects.

Evolution of the IgE and IgG repertoire to a comprehensive array of allergen molecules in the first decade of life.  
Huang X, Tsilochristou O, Perna S, Hofmaier S, Cappella A, Bauer CP, Hoffman U, Forster J, Zepp F, Schuster A, D'Amelio R, Wahn U, Keil T, Lau S, Matricardi PM.
Allergy 2017 Aug 8;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Characteristics of severe asthma with fungal sensitization.
This study investigated the clinical characteristics of severe asthma with fungal sensitization. The study enrolled 124 patients with severe asthma. Thirty-six patients (29%) showed sensitization to at least 1 fungal allergen. The most common species were Candida (16%), Aspergillus (11%), and Trichophyton (11%). The rate of early-onset asthma (<16 years of age) was higher in patients with fungal sensitization than in those without fungal sensitization. Interleukin-33 levels were higher in patients with fungal sensitization than in those without fungal sensitization.

Characteristics of severe asthma with fungal sensitization.  
Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, U.
Ann Allergy Asthma Immunol 2017 Aug 8;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Food allergen extracts to diagnose food-induced allergic diseases: How they are made.
This article reviews the manufacturing procedures of food allergen extracts and applicable regulatory requirements from government agencies, potential approaches to standardization, and clinical application of these products. The effects of thermal processing on allergenicity of common food allergens are also considered. The manufacture of food allergen extracts requires many considerations to achieve the maximal quality of the final product. Allergen extracts for a select number of foods may be inconsistent between manufacturers or unreliable in a clinical setting, indicating a potential area for future improvement

Food allergen extracts to diagnose food-induced allergic diseases: How they are made.  
David NA, Penumarti A, Burks AW, Slater JE.
Ann Allergy Asthma Immunol 2017 Aug;119(2):101-107

Click to view abstract

Index
Allergy and Intolerance Abstracts
Solenopsis geminata (tropical fire ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.
This study characterized ant species causing anaphylaxis in Thai patients and tested allergenic reactivity to whole body extracts (WBE) of S. geminata (tropical fire ants) in patients with evidence of IgE-mediated ant anaphylaxis. Thirty-two patients with ant anaphylaxis were identified. Of 32 patients with ant anaphylaxis, the most common causative ant identified was S. geminata (37.5%). Western blot analysis of crude S. geminata revealed 13 refined protein components that bound to patients' serum IgE. Three major allergens with molecular masses of 26, 55 and 75 kDa were identified. All 12 patients gave positive results for specific IgE to S. geminata with statistically significant higher absorbance units of 0.390 +/- 0.044, compared to healthy control group (0.121 +/- 0.010), P < 0.01.

Solenopsis geminata (tropical fire ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.  
Potiwat R, Tanyaratsrisakul S, Maneewatchararangsri S, Manuyakorn W, Rerkpattanapipat T, Samung Y, Sirivichayakul C, Chaicumpa W, Sitcharungsi R.
Asian Pac J Allergy Immunol 2017 Aug 8;

Click to view abstract

Index
Allergy and Intolerance Abstracts
The role of environmental exposure to peanut in the development of clinical allergy to peanut.
The presence of peanut allergy has increased over the years and still remains one of the most common causes of food-related anaphylaxis. The way in which peanut sensitization occurs has been explored, such as via maternal consumption in pregnancy, via breast milk and through a disrupted skin barrier. It has previously been shown that environmental exposure to aeroallergens in household dust can be a risk factor for the development of allergic asthma. However, it is likely that the combination of cutaneous sensitisation via a disrupted skin barrier (i.e. children with eczema especially those with filaggrin mutations) and the interaction with environmental peanut exposure influences the development of peanut allergy. This review aims to explore the current evidence of how environmental exposure to peanut affects the development of peanut allergy.

The role of environmental exposure to peanut in the development of clinical allergy to peanut.  
Foong RX, Brough H.
Clin Exp Allergy 2017 Aug 5;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Update on Quinolone Allergy.
Allergic reactions to quinolones can be immediate or delayed, being anaphylaxis and maculopapular exanthema respectively the most frequent clinical entities. A precise diagnosis is particularly difficult since clinical history is often unreliable, skin tests can induce false-positive results, and commercial in vitro test are not well validated. Therefore, drug provocation testing is considered the gold standard to establish diagnosis, which is not a risk-free procedure. Cross-reactivity between quinolones is difficult to predict due to the small number of patients included in the few published studies. Moreover, hypersensitivity to quinolones has also been associated with beta-lactam and neuromuscular blocking agent allergies, although further studies are needed to understand the underlying mechanisms. Avoidance of the culprit quinolone is indicated in patients with a diagnosis of hypersensitivity to these drugs. When quinolone treatment is the only therapeutic option available, desensitization is necessary. This review summarizes the complex diagnostic approach and management of allergic reactions to quinolones

Update on Quinolone Allergy.  
Dona I, Moreno E, Perez-Sanchez N, Andreu I, Hernandez Fernandez de RD, Torres MJ.
Curr Allergy Asthma Rep 2017 Aug;17(8):56

Click to view abstract

Index
Allergy and Intolerance Abstracts
Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder?
Although hymenoptera-induced anaphylaxis is not primarily a mast cell-driven hematological disorder, the latter is present in a significant proportion of patients and has to be excluded by basal serum tryptase determination, skin inspection as well as exclusion of systemic mastocytosis by D816V mutation analysis in peripheral blood and/or bone marrow examination in selected patients

Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder?  
Brockow K, Akin C.
Curr Opin Allergy Clin Immunol 2017 Aug 8;

Click to view abstract

Index
Allergy and Intolerance Abstracts
The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.
Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies requires the engagement of key stakeholders such as allergists, immunologists, pharmacists, and infectious diseases physicians. To help address this burden of antibiotic allergy overlabeling, we review 3 key antibiotic allergy domains: (1) antibiotic allergy classification, (2) antibiotic cross-reactivity, and (3) multidisciplinary collaboration. We review the available evidence and research gaps of currently used adverse drug reaction classification systems, antibiotic allergy cross-reactivity, and current and future models of antibiotic allergy care

The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.  
Trubiano JA, Stone CA, Lindsay GM, Urbancic K, Slavin MA, Thursky KA, Phillips EJ.
J Allergy Clin Immunol Pract 2017 Aug 23;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Risk of allergic reactions to recurrent intravenous penicillin administration in penicillin skin test negative patients.
In patients who report penicillin allergy and have negative penicillin allergy testing, repeated administration of intravenous penicillin antibiotics appears to be safe. Larger prospective studies should be performed to confirm these observations

Risk of allergic reactions to recurrent intravenous penicillin administration in penicillin skin test negative patients.  
Dorman SM, Seth S, Khan DA.
J Allergy Clin Immunol Pract 2017 Aug 9;

Click to view abstract

Index

Allergen-, Food allergy-, Intolerance-related articles

Evolution of the IgE and IgG repertoire to a comprehensive array of allergen molecules in the first decade of life.  
Huang X, Tsilochristou O, Perna S, Hofmaier S, Cappella A, Bauer CP, Hoffman U, Forster J, Zepp F, Schuster A, D'Amelio R, Wahn U, Keil T, Lau S, Matricardi PM.
Allergy 2017 Aug 8;
Click to view abstract

Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'.  
Lawson K, Bahnson HT, Brittain E, Sever M, Du Toit G, Lack G, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J.
Allergy 2017 Aug;72(8):1267-1271

Poor sleep is highly associated with house dust mite allergic rhinitis in adults and children.  
Leger D, Bonnefoy B, Pigearias B, de La GB, Chartier A.
Allergy Asthma Clin Immunol 2017;1336
Click to view abstract

Characteristics of severe asthma with fungal sensitization.  
Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, U.
Ann Allergy Asthma Immunol 2017 Aug 8;
Click to view abstract

Adult-onset food allergies.  
Ramesh M, Lieberman JA.
Ann Allergy Asthma Immunol 2017 Aug;119(2):111-119

Food allergen extracts to diagnose food-induced allergic diseases: How they are made.  
David NA, Penumarti A, Burks AW, Slater JE.
Ann Allergy Asthma Immunol 2017 Aug;119(2):101-107
Click to view abstract

Frequency of self-reported drug allergy: A systematic review and meta-analysis with meta-regression.  
Sousa-Pinto B, Fonseca JA, Gomes ER.
Ann Allergy Asthma Immunol 2017 Aug 2;
Click to view abstract

Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults.  
Bedolla-Barajas M, Puente-Fernandez C, Flores-Merino MV, Morales-Romero J, Dominguez-Garcia MV.
Asia Pac Allergy 2017 Jul;7(3):156-162
Click to view abstract

A review of 42 asthmatic children with allergic bronchopulmonary aspergillosis.  
Shah A, Kunal S.
Asia Pac Allergy 2017 Jul;7(3):148-155
Click to view abstract

Solenopsis geminata (tropical fire ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.  
Potiwat R, Tanyaratsrisakul S, Maneewatchararangsri S, Manuyakorn W, Rerkpattanapipat T, Samung Y, Sirivichayakul C, Chaicumpa W, Sitcharungsi R.
Asian Pac J Allergy Immunol 2017 Aug 8;
Click to view abstract

Immediate hypersensitivity reaction to Ketamine in children with history of atopic disease.  
Ki S, Lim S, Kim MH, Kim Y.
Asian Pac J Allergy Immunol 2017 Aug 8;
Click to view abstract

Quality of life among caregivers and growth in children with parent-reported food allergy.  
Kajornrattana T, Sangsupawanich P, Yuenyongviwat A.
Asian Pac J Allergy Immunol 2017 Aug 8;
Click to view abstract

Allergic sensitization to laboratory animals is more associated with asthma, rhinitis and skin symptoms than sensitization to common allergens.  
Simoneti CS, Ferraz E, de Menezes MB, Bagatin E, Arruda LK, Vianna EO.
Clin Exp Allergy 2017 Aug 8;
Click to view abstract

Association between infection with H. pylori and atopy in young Ethiopian Children: a longitudinal study.  
Taye B, Enquselassie F, Tsegaye A, Amberbir A, Medhin G, Fogarty A, Robinson K, Davey G.
Clin Exp Allergy 2017 Aug 8;
Click to view abstract

The role of environmental exposure to peanut in the development of clinical allergy to peanut.  
Foong RX, Brough H.
Clin Exp Allergy 2017 Aug 5;
Click to view abstract

Hydrolysed ovalbumin offers more effective preventive and therapeutic protection against egg allergy than the intact protein.  
Lozano-Ojalvo D, Perez-Rodriguez L, Pablos-Tanarro A, Molina E, Lopez-Fandino R.
Clin Exp Allergy 2017 Aug 1;
Click to view abstract

A critical analysis of the utility of component tests in the diagnosis of pollen-related peanut and hazelnut allergy in the context of the BSACI guideline.  
Beck S, Huissoon AP, Baretto RL, Krishna MT.
Clin Exp Allergy 2017 Aug 1;
Click to view abstract

A new approach to specific IgE testing, asthma and auto-injectors in schools.  
Roberts G.
Clin Exp Allergy 2017 Aug;47(8):986-987

Relevance of lipophilic allergens in food allergy diagnosis.  
Jappe U, Schwager C.
Curr Allergy Asthma Rep 2017 Aug 9;17(9):61
Click to view abstract

Diagnosis of allergy to mammals and fish: Cross-reactive vs. specific markers.  
Hilger C, van HM, Kuehn A.
Curr Allergy Asthma Rep 2017 Aug 22;17(9):64
Click to view abstract

Update on Quinolone Allergy.  
Dona I, Moreno E, Perez-Sanchez N, Andreu I, Hernandez Fernandez de RD, Torres MJ.
Curr Allergy Asthma Rep 2017 Aug;17(8):56
Click to view abstract

Tobacco Use and Smoke Exposure in Children: New Trends, Harm, and Strategies to Improve Health Outcomes.  
Makadia LD, Roper PJ, Andrews JO, Tingen MS.
Curr Allergy Asthma Rep 2017 Aug;17(8):55
Click to view abstract

Eosinophilic Esophagitis in Children.  
Ruffner MA, Spergel JM.
Curr Allergy Asthma Rep 2017 Aug;17(8):54
Click to view abstract

Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder?  
Brockow K, Akin C.
Curr Opin Allergy Clin Immunol 2017 Aug 8;
Click to view abstract

Climate changes and Hymenoptera venom allergy: are there some connections?  
Turillazzi S, Turillazzi F.
Curr Opin Allergy Clin Immunol 2017 Aug 8;
Click to view abstract

Do advanced glycation end-products cause food allergy?  
Smith PK.
Curr Opin Allergy Clin Immunol 2017 Aug 3;
Click to view abstract

Hypersensitivity reactions to gadolinium-based contrast agents.  
Fok JS, Smith WB.
Curr Opin Allergy Clin Immunol 2017 Aug;17(4):241-246
Click to view abstract

Molecular Recognition Profiles and Clinical Patterns of PR-10 Sensitization in a Birch-Free Mediterranean Area.  
Scala E, Abeni D, Cecchi L, Guerra EC, Locanto M, Pirrotta L, Giani M, Asero R.
Int Arch Allergy Immunol 2017 Aug 9;173(3):138-146
Click to view abstract

Association between caesarean delivery and isolated doses of formula feeding in cow milk allergy.  
Gil F, Amezqueta A, Martinez D, Aznal E, Etayo V, Dura T, Sanchez-Valverde F.
Int Arch Allergy Immunol 2017 Aug 9;173(3):147-152
Click to view abstract

The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.  
Trubiano JA, Stone CA, Lindsay GM, Urbancic K, Slavin MA, Thursky KA, Phillips EJ.
J Allergy Clin Immunol Pract 2017 Aug 23;
Click to view abstract

Bullous Fixed Drug Eruption Secondary to Chlorthalidone.  
Cuervo-Pardo N, Gonzalez-Estrada A, Cuervo-Pardo L, Reddy K, Gonzalez-Estrada A.
J Allergy Clin Immunol Pract 2017 Aug 12;

Risk of allergic reactions to recurrent intravenous penicillin administration in penicillin skin test negative patients.  
Dorman SM, Seth S, Khan DA.
J Allergy Clin Immunol Pract 2017 Aug 9;
Click to view abstract

Blue dye allergy: Pitfalls in diagnosis and how to avoid them.  
Li PH, Wagner A, York M, Rutkowski R, Haque R, Rutkowski K.
J Allergy Clin Immunol Pract 2017 Aug 9;

FPIES: not so rare after all!.  
Nowak-Wegrzyn A, Spergel JM.
J Allergy Clin Immunol 2017 Aug 7;

Peanut-free schools: What does it really mean, and are they necessary?  
Stukus DR.
J Allergy Clin Immunol 2017 Aug;140(2):391-392

Impact of school peanut-free policies on epinephrine administration.  
Bartnikas LM, Huffaker MF, Sheehan WJ, Kanchongkittiphon W, Petty CR, Leibowitz R, Hauptman M, Young MC, Phipatanakul W.
J Allergy Clin Immunol 2017 Aug;140(2):465-473
Click to view abstract

Immunologic study of two fruit-induced FPIES cases.  
Moreno MV, Caparros E, Fernandez J, Gonzalez-Delgado P.
Pediatr Allergy Immunol 2017 Aug 8;
Click to view abstract

Food-induced anaphylaxis to a known food allergen in children often occurs despite adult supervision.  
De SS, Clarke A, La VS, Eisman H, Morris J, Lim R, Gravel J, Ben-Shoshan M.
Pediatr Allergy Immunol 2017 Aug 8;
Click to view abstract

Sensitization to dust mite defines different phenotypes of asthma: a multicenter study.  
Ruggieri S, Drago G, Longo V, Colombo P, Balzan M, Bilocca D, Zammit C, Montefort S, Scaccianoce G, Cuttitta G, Viegi G, Cibella F.
Pediatr Allergy Immunol 2017 Aug 7;
Click to view abstract

Should lip dosing be reconsidered when performing open food challenges?  
Venter C, Maslin K, Grundy J, Glasbey G, Dean T.
Pediatr Allergy Immunol 2017 Aug 7;
Click to view abstract

Vaccination and allergy: EAACI position paper, practical aspects.  
Nilsson L, Brockow K, Alm J, Cardona V, Caubet JC, Gomes E, Jenmalm MC, Lau S, Netterlid E, Schwarze J, Sheikh A, Storsaeter J, Skevaki C, Terreehorst I, Zanoni G.
Pediatr Allergy Immunol 2017 Aug 4;
Click to view abstract


Previous Issues of Allergy Advisor Digest
January 2010   February 2010   March 2010   April 2010   May 2010   June 2010   July 2010   August 2010   September 2010   October 2010   November 2010   December 2010   January 2011   February 2011   March 2011   April 2011   May 2011   June 2011   July 2011   August 2011   September 2011   October 2011   November 2011   December 2011   January 2012   February 2012   March 2012   April 2012   May 2012   June 2012   July 2012   August 2012   September 2012   October 2012   November 2012   December 2012   January 2013   February 2013   March 2013   April 2013   May 2013   June 2013   July 2013   August 2013   September 2013   October 2013   November 2013   December 2013   January 2014   February 2014   March 2014   April 2014   May 2014   June 2014   July 2014   August 2014   September 2014   October 2014   November 2014   December 2014   January 2015   February 2015   March 2015   April 2015   May 2015   June 2015   July 2015   August 2015   September 2015   October 2015   November 2015   December 2015   January 2016   February 2016   March 2016   April 2016   May 2016   June 2016   July 2016   August 2016   September 2016   October 2016   November 2016   December 2016   January 2017   February 2017   March 2017   April 2017   May 2017   June 2017   July 2017   August 2017   September 2017  


To subscribe to future Digest installments , subscribe here, and we will notify you when the new Digest is published.


Allergy and Intolerance Information