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 Allergy Advisor Digest - June 2016
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Snippets NOT posted in the June 2016 Advisor Digest Newsletter

Read Measurement of the air concentration of terpene VOCs (including limonene) according to several procedures when spraying a mixture of essential oils.
Read Cross sectional questionnaire-based internet study: Self-perception and clinical course of drug allergy in Greece.
Read Hymenoptera stings in the head region induce impressive, but not severe sting reactions.
Read Introduction of peanuts in younger siblings of children with peanut allergy: a prospective, double-blinded assessment of risk, of diagnostic tests and an analysis of patient preferences.
Read The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.
Read Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort.
Read Diagnoses and Management of Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: Reactions to Taxanes and Monoclonal Antibodies.
Read Transglutaminase 2 and transglutaminase 2 autoantibodies in celiac disease: a review.
Read Doctor, my child is bullied: food allergy management in schools.
Read Are genetic tests informative in predicting food allergy?
Read Identification and characterization of IgE-Binding tropomyosins in Aedes aegypti.
Read Food protein-induced enterocolitis syndrome in two exclusively breastfed infants.
Read A comparative analysis between antibiotic- and nonantibiotic-associated delayed cutaneous adverse drug reactions.
Read Sensitization of a child to Cyanobacteria after recreational swimming in a lake.

Snippets posted in the June 2016 Advisor Digest Newsletter

Read Camel milk: new source of protein for children allergic to cow's milk protein?
Read Cross-reactivity to fish and chicken meat - a new clinical syndrome.
Read Hypersensitivities to sesame and other common edible seeds.
Read The quantity and quality of alpha-gal-specific antibodies differs in individuals with and without delayed red meat allergy.
Read Increased pain and muscle glutamate concentration after single ingestion of monosodium glutamate by myofascial temporomandibular disorders patients.
Read Anaphylactic reaction after ongoing exposure to hair glue
Read A retrospect study into the utility of allergen components in walnut allergy.
Read Detection of major food allergens in amniotic fluid: initial allergenic encounter during pregnancy.
Read Anaphylactic shock caused by a hidden allergen in blood sausage.
Read Nonoccupational airborne-induced anaphylaxis caused by Anisakis simplex.

Allergy and Intolerance Abstracts
Measurement of the air concentration of terpene VOCs (including limonene) according to several procedures when spraying a mixture of essential oils.
Essential oils are used more and more to fight against allergens, and they are sometimes recommended for that purpose by manufacturers. The aim of this study was to measure the concentration of limonene in ambient air after spraying a mixture of 41 essential oils. We have demonstrated with three different methods that spraying an essential oils mixture resulted in an increase of airborne VOCs and limonene higher than normal values. According to the literature, high total VOC concentrations above the standard values are harmful for patients with asthma. Consequently, spraying essential oils mixtures should not be recommended for asthmatic patients.

Measurement of the air concentration of terpene VOCs (including limonene) according to several procedures when spraying a mixture of essential oils. [French]  
C. Delmas, A.-S. Weiler, S. Ortega, O. Duong, A. Dazy, Mr. Ott, C. Schneider, R. Moritz, N. Leclerc, E. River, F. de Blay
Rev Fr Allergol 2016;56(4):357-363

Click to view abstract Click to view abstract

Index
Allergy and Intolerance Abstracts
Cross sectional questionnaire-based internet study: Self-perception and clinical course of drug allergy in Greece.
Allergic reactions to drugs are adverse events difficult to define and diagnose. A remarkable proportion of presumed as hypersensitivity reactions are not referred to allergists; therefore these patients may be either re-exposed to potentially noxious drugs, or needlessly avoid whole classes of drugs as b-lactams for more costly or less appropriate treatments. Internet-based questionnaires may contribute to awareness programs concerning drug allergy and help improve proper referral

Cross sectional questionnaire-based internet study: Self-perception and clinical course of drug allergy in Greece.  
Makris MP, Sergentanis TN, Aggelides X, Tzanninis S, Polyzou E, Rigopoulos D, Psaltopoulou T.
Allergol Int 2016 Jun 11;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Hymenoptera stings in the head region induce impressive, but not severe sting reactions.
Stings in the head region are considered to be a risk factor for severe systemic reactions to Hymenoptera stings. We supposed that stings in skin areas, which are well supplied with blood, lead to more severe reactions and tested our hypothesis in 847 patients with confirmed Hymenoptera venom allergy. However, symptom severity was independent from sting site: only 16.3% of patients with severe reactions were stung on the head. But we confirmed age > 40 years as well as elevated basal tryptase levels as risk factors.

Hymenoptera stings in the head region induce impressive, but not severe sting reactions.  
Arzt L, Bokanovic D, Schwarz I, Schrautzer C, Massone C, Horn M, Aberer W, Sturm G.
Allergy 2016 Jun 27;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Introduction of peanuts in younger siblings of children with peanut allergy: a prospective, double-blinded assessment of risk, of diagnostic tests and an analysis of patient preferences.
The prevalence of peanut allergy in younger siblings of children with peanut allergy has been reported between 7 to 8.5%, but the anaphylactic risk at time of introduction is currently unknown, which limits our ability to best counsel parents on this issue. This study determined the risk of anaphylaxis and working parameters of allergy testing in this context. 154 peanut-naive younger siblings of peanut allergic children underwent double-blinded skin testing, followed by parent-led peanut introduction. Eight participants (5.2%) presented unequivocal IgE-mediated reactions to peanut upon introduction, including 5 anaphylaxes. These participants were significantly older compared to the rest of the cohort (median 4.0 vs 1.9 y). The negative predictive value of SPT with peanut extract and peanut butter and of specific IgE was 99%, 100% and 100%, respectively. Six peanut tolerant participants had positive peanut allergy tests.

Introduction of peanuts in younger siblings of children with peanut allergy: a prospective, double-blinded assessment of risk, of diagnostic tests and an analysis of patient preferences.  
Begin P, Graham F, Killer K, Paradis J, Paradis L, Des RA.
Allergy 2016 Jun 13;

Click to view abstract

Index
Allergy and Intolerance Abstracts
The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.
The prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenicity and cross-reactivity with the dog lipocalin Can f 1 was assessed. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation between IgE levels to rFel d 7 and rCan f 1 was found. rFel d 7 activated basophils in vitro and inhibited IgE-binding to rCan f 1 in 4/13 patients, whereas rCan f 1 inhibited IgE-binding to rFel d 7 in 7/13 patients. Fel d 7 and Can f 1 showed high similarities in protein structure and epitopes in common were found by using cross-reactive antisera. Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1, and may contribute to symptoms in cat- but also in dog-allergic patients.

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.  
Apostolovic D, Sanchez-Vidaurre S, Waden K, Curin M, Grundstrom J, Gafvelin G, Cirkovic VT, Gronlund H, Thomas W, Valenta R, Hamsten C, van HM.
Allergy 2016 Jun 11;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort.
Patients often report adverse reactions to wheat. Interpretation of sensitization to wheat pollen and flour with/without sensitization to grass pollen is a clinical problem. We set out to determine the prevalence of wheat allergy in a birth cohort (10/11 year olds) and investigate the usefulness of performing skin prick tests (SPT), specific IgE tests and component resolved diagnostics to wheat pollen and flour. Eight children underwent oral food challenges (OFC). We diagnosed 0.48 % (4/827; 95 % CI 0-1 %) children with wheat allergy based on OFC. 16.3 % (96/588) were sensitized to grass pollen, 13.4 % (79/588) to wheat pollen; 78 % (75/96) sensitized to both. Only one child was sensitized to wheat flour and wheat pollen, but not grass pollen. For specific IgE, 15.0 % (37/246) and 36.2 % (89/246) were sensitized to wheat and grass pollen, with 40.5 % (36/89) sensitized to both. Of the 37 children sensitized to wheat, 3 (8.1 %) were sensitized to omega 5 gliadin, 1 (2.7 %) to wheat lipid transfer protein and 1 to wheat gliadin. Clinicians should be aware of the high level of cross-sensitization when performing tests to wheat and grass pollen i.e. sensitisation to wheat specific IgE and wheat pollen SPT should be assessed in the presence of grass pollen SPT and/or specific IgE

Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort.  
Venter C, Maslin K, Arshad SH, Patil V, Grundy J, Glasbey G, Twiselton R, Dean T.
Clin Transl Allergy 2016;622

Click to view abstract

Index
Allergy and Intolerance Abstracts
Diagnoses and Management of Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: Reactions to Taxanes and Monoclonal Antibodies.
The aim of this review is to provide an update on hypersensitivity reactions to commonly used monoclonal and taxanes, their clinical presentations, diagnosis, and the use of RDD for their management

Diagnoses and management of drug hypersensitivity and anaphylaxis in cancer and chronic inflammatory diseases: reactions to taxanes and monoclonal antibodies.  
Bonamichi-Santos R, Castells M.
Clin Rev Allergy Immunol 2016 Jun 8;

Index
Allergy and Intolerance Abstracts
Transglutaminase 2 and transglutaminase 2 autoantibodies in celiac disease: a review.
"Celiac disease is a common inflammatory disorder with a prevalence of 1-2 % in which a distinct dietary wheat, rye, and barley component, gluten, induces small-bowel mucosal villous atrophy, crypt hyperplasia, and inflammation. The small-bowel mucosal damage can be reversed by a strict lifelong gluten-free diet, which is currently the only effective treatment for the condition. A key player in the pathogenetic process leading to the enteropathy is played by a protein called transglutaminase 2 (TG2), which is able to enzymatically modify gluten-derived gliadin peptides. The TG2-catalyzed deamidation of the gliadin peptides results in their increased binding affinity to the disease-predisposing human leukocyte antigen (HLA) DQ2 and DQ8 molecules, thus enabling a strong immune response to be launched. Blocking the enzymatic activity of TG2 has thus been suggested as a suitable novel pharmacological approach to treat celiac disease. By virtue of its transamidation capacity, TG2 is also able to cross-link gliadin peptides to itself, this resulting in the generation of TG2-gliadin peptide complexes whose presence might provide an explanation for the generation of the TG2 autoantibodies characteristic of celiac disease. Due to their excellent specificity for the disorder, the TG2-targeted autoantibodies are widely used in the diagnostics as a first-line test to select patients for gastrointestinal endoscopy. More recently, it has come to be appreciated that these autoantibodies and also the TG2-specific B cells might play an active role in the disease pathogenesis. In this review, we assess the role of TG2, TG2-specific B cells, and autoantibodies in celiac disease."

Transglutaminase 2 and transglutaminase 2 autoantibodies in celiac disease: a review.  
Rauhavirta T, Hietikko M, Salmi T, Lindfors K.
Clin Rev Allergy Immunol 2016 Jun 4;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Doctor, my child is bullied: food allergy management in schools.
Current recommendations for food allergy management in schools focus on appropriate avoidance measures and prompt recognition and treatment of allergic reactions. Guidelines focus upon a school-wide approach, with comprehensive involvement of many stakeholders, but individual students require specific emergency action plans. Special risk groups include young children who need additional supervision and adolescents who may take risks. Based on the observation that anaphylaxis can occur in persons without a prior diagnosis, having epinephrine available for prompt first-aid management of any student in need is now recommended. To promote socialization, avoidance measures should minimize separation of children with food allergies from their peers. Parents and schools need to be aware of bullying and implement intervention and prevention measures.

Doctor, my child is bullied: food allergy management in schools.  
Egan M, Sicherer S.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):291-296

Click to view abstract

Index
Allergy and Intolerance Abstracts
Are genetic tests informative in predicting food allergy?
With the advance of high-throughput genotyping and sequencing techniques together with improved analytical methods, the contributions of genetic and environmental factors in development of food allergy are being clarified. Yet much remains to be explored and more studies with larger sample sizes, better phenotyping, and improved quality control genomics methods are needed. The ultimate goal is the development of a panel of reliable markers for genetic testing in food allergy to improve overall patient care

Are genetic tests informative in predicting food allergy?  
Li J, Maggadottir SM, Hakonarson H.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):257-264

Click to view abstract

Index
Allergy and Intolerance Abstracts
Identification and characterization of IgE-Binding tropomyosins in Aedes aegypti.
Natural wild-type mosquito tropomyosin was purified from an A. aegypti extract. Two recombinant variants of tropomyosin were obtained by expression. Four variants of natural tropomyosin were purified. A band of 32 kDa representing 2 tropomyosin variants (Aed a 10.0101 and Aed a 10.0201) reacted with specific IgE of 4 of the 12 (33%) allergic patients and with rabbit polyclonal anti-shrimp tropomyosin. A high degree of cross-reactivity (60-70%) was detected between natural mosquito tropomyosin and Blo t 10, Der p 10 and Lit v 1, and a lower degree with Asc l 3 from A. lumbricoides (<30%).

Identification and characterization of IgE-Binding tropomyosins in Aedes aegypti.  
Cantillo JF, Puerta L, Lafosse-Marin S, Subiza JL, Caraballo L, Fernandez-Caldas E.
Int Arch Allergy Immunol 2016 Jun 30;170(1):46-56

Click to view abstract

Index
Allergy and Intolerance Abstracts
Food protein-induced enterocolitis syndrome in two exclusively breastfed infants.
A report of two cases of FPIES described even in exclusively breast-fed infants in which symptoms occurred after maternal ingestion of cow's milk.

Food protein-induced enterocolitis syndrome in two exclusively breastfed infants.  
Kaya A, Toyran M, Civelek E, Misirlioglu ED, Kirsaclioglu CT, Kocabas CN.
Pediatr Allergy Immunol 2016 Jun 11;

Click to view abstract

Index
Allergy and Intolerance Abstracts
A comparative analysis between antibiotic- and nonantibiotic-associated delayed cutaneous adverse drug reactions.
The difference in clinical presentation, causality assessments, and outcomes of patients with delayed antibiotic-associated cutaneous adverse drug reactions (AA-cADR) and nonantibiotic-associated (NA)-cADR is ill defined. The authors examined the etiology of AA-cADR, with regard to the type of antibiotic exposure, allergy labeling, and patient outcomes, in comparison with NA-cADR. They conclude that antibiotics were the cause of cADR requiring hospital admission in 48% of episodes, and were associated with longer length of stay, higher age-adjusted Charlson comorbidity index, shorter drug latency, and mortality. In AA-cADR, glycopeptide and sulfonamide antibiotic exposure predominated

A comparative analysis between antibiotic- and nonantibiotic-associated delayed cutaneous adverse drug reactions.  
Trubiano JA, Aung AK, Nguyen M, Fehily SR, Graudins L, Cleland H, Padiglione A, Peleg AY.
J Allergy Clin Immunol Pract 2016 Jun 7;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Sensitization of a child to Cyanobacteria after recreational swimming in a lake.
A case of an 11-year-old white girl who had an allergic reaction manifesting as severe facial swelling with periorbital edema and an erythematous pruritic blistering rash over her arms and hands (Fig 1) after playing and swimming in Lake Ontario at Presque Isle State Park. After repeated handling of algae making “bird's nests,” the patient put sunscreen on her arms and face and then went swimming in the lake for 20 minutes. The exact time of the onset of the reaction is unknown because it began a few hours after she went to sleep. The next morning, she awoke with erythematous itchy swollen arms, face, and eyes and over time had facial and periorbital edema. Soon thereafter, she lost consciousness for approximately 30 seconds. One day after discontinuing the corticosteroids, approximately 8 days after the initial reaction, she experienced itching, and blisters appeared on her hands. A serum sample showed increased specific IgE levels to Cyanobacteria extract. Because all Cyanobacteria species produce phycocyanin, we investigated whether the patient was sensitized to 1 or more species of Cyanobacteria. Cross-reactivity to multiple Cyanobacteria species and selective inhibition assays indicates that phycocyanin is the major protein eliciting these allergic reactions.

Sensitization of a child to Cyanobacteria after recreational swimming in a lake.  
Geh EN, de la Cruz AA, Ghosh D, Stelma G, Bernstein JA.
J Allergy Clin Immunol 2016 Jun;137(6):1902-1904

Index

Allergen-, Food allergy-, Intolerance-related articles

Pollution intérieure : comment améliorer la qualité de l’air ? / Indoor Pollution: How to improve air quality?  
F. Lavaud, G. Dutau
Rev Fr Allergol 2016;56(4):41-343
Click to view abstract Click to view abstract

Lait camelin : nouvelle source de protéines pour enfants allergiques aux protéines du lait de vache ? / Camel milk: new source of protein for children allergic to cow's milk protein?  
H. Boughellout, Y. Choiset, H. Rabesona, J.M. Chobert, T. Haertle, M.N. Zidoune
Rev Fr Allergol 2016;56(4):344-348
Click to view abstract Click to view abstract

Can we predict the positive allergic skin tests in case of increase of fractional exhaled nitric oxide in the suspect asthma child? [French]  
M. Thimmesch, E. Bodart
Rev Fr Allergol 2016;56(4):349-356
Click to view abstract Click to view abstract

Measurement of the air concentration of terpene VOCs (including limonene) according to several procedures when spraying a mixture of essential oils. [French]  
C. Delmas, A.-S. Weiler, S. Ortega, O. Duong, A. Dazy, Mr. Ott, C. Schneider, R. Moritz, N. Leclerc, E. River, F. de Blay
Rev Fr Allergol 2016;56(4):357-363
Click to view abstract Click to view abstract

Y-a-t-il un rationnel pour conseiller des cosmétiques « sans » ? / Are there a rational advisor for cosmetics "no"?  
F. Castelain, F. Pelletier, P. Girardin, Mr Vigan
Rev Fr Allergol 2016;56(4):389-390
Click to view abstract Click to view abstract

Transport des allergènes par les acariens / Transport of mite allergens  
G. Reboux, A. Naegele, S. Roussel, L. Millon
Rev Fr Allergol 2016;56(4):393-394
Click to view abstract Click to view abstract

Le test de réintroduction : ses modalités en fonction du phénotype de l’allergie alimentaire / The reintroduction test: according to its terms food allergy phenotype  
V. Jubin
Rev Fr Allergol 2016;56(4):395-397
Click to view abstract Click to view abstract

Delayed urticaria due to bupivacaine: A new presentation of local anesthetic allergy.  
Vega F, Argiz L, Bazire R, Las HP, Blanco C.
Allergol Int 2016 Jun 16;

Cross sectional questionnaire-based internet study: Self-perception and clinical course of drug allergy in Greece.  
Makris MP, Sergentanis TN, Aggelides X, Tzanninis S, Polyzou E, Rigopoulos D, Psaltopoulou T.
Allergol Int 2016 Jun 11;
Click to view abstract

Hymenoptera stings in the head region induce impressive, but not severe sting reactions.  
Arzt L, Bokanovic D, Schwarz I, Schrautzer C, Massone C, Horn M, Aberer W, Sturm G.
Allergy 2016 Jun 27;
Click to view abstract

Cross-reactivity to fish and chicken meat - a new clinical syndrome.  
Kuehn A, Morel-Codreanu F, Lehners-Weber C, Doyen V, Gomez-Andre SA, Bienvenu F, Fischer J, Ballardini N, van HM, Perotin JM, Silcret-Grieu S, Chabane H, Hentges F, Ollert M, Hilger C, Mo.
Allergy 2016 Jun 27;

Introduction of peanuts in younger siblings of children with peanut allergy: a prospective, double-blinded assessment of risk, of diagnostic tests and an analysis of patient preferences.  
Begin P, Graham F, Killer K, Paradis J, Paradis L, Des RA.
Allergy 2016 Jun 13;
Click to view abstract

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.  
Apostolovic D, Sanchez-Vidaurre S, Waden K, Curin M, Grundstrom J, Gafvelin G, Cirkovic VT, Gronlund H, Thomas W, Valenta R, Hamsten C, van HM.
Allergy 2016 Jun 11;
Click to view abstract

Mold-sensitised adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitised to other aeroallergens.  
Matheson MC, Reece JC, Kandane-Rathnayake RK, Tang ML, Simpson JA, Feather IH, Southey MC, Tsimiklis H, Hopper JL, Morrison SC, Giles GG, Walters EH, Dharmage SC.
Allergy 2016 Jun 22;
Click to view abstract

Hypersensitivities to sesame and other common edible seeds.  
Patel A, Bahna SL.
Allergy 2016 Jun 22;
Click to view abstract

Precautionary Allergy Labelling: NO MORE TRACES!.  
Turner PJ, Gowland MH.
Allergy 2016 Jun 20;
Click to view abstract

The quantity and quality of alpha-gal-specific antibodies differs in individuals with and without delayed red meat allergy.  
Kollmann D, Nagl B, Ebner C, Emminger W, Wohrl S, Kitzmuller C, Vrtala S, Mangold A, Ankersmit HJ, Bohle B.
Allergy 2016 Jun 4;
Click to view abstract

Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber.  
Lueer K, Biller H, Casper A, Windt H, Mueller M, Badorrek P, Haefner D, Framke T, Koch A, Ziehr H, Krug N, Koch W, Hohlfeld JM.
Allergy 2016 Jun 3;
Click to view abstract

Comparison of ImmunoCAP and Immulite serum specific IgE assays for the assessment of egg allergy.  
Graham F, Begin P, Paradis L, Lacombe-Barrios J, Paradis J, Des RA.
Allergy Asthma Clin Immunol 2016;1229
Click to view abstract

Approach to food allergy diagnosis and management by nonspecialty practitioners.  
Welch K, Chokshi N, Wang J.
Ann Allergy Asthma Immunol 2016 Jun;116(6):585-588

Social media and the allergy practice.  
Dimov V, Gonzalez-Estrada A, Eidelman F.
Ann Allergy Asthma Immunol 2016 Jun;116(6):484-490

Summer camps and food allergy: What do we not know?  
Lieberman JA.
Ann Allergy Asthma Immunol 2016 Jun;116(6):482-483

Novel application of the controlled allergen challenge facility model.  
Ellis AK.
Ann Allergy Asthma Immunol 2016 Jun;116(6):481-482

Coronary spasm secondary to biphasic anaphylaxis after hymenoptera stings.  
Blasco-Navalpotro MA, Orejas-Gallego A, Flordelis-Lasierra JL, Prior-Gomez N, Jimenez-Jimenez J, Seoane-Leston FJ.
Ann Allergy Asthma Immunol 2016 Jun 1;

Persistent nasal symptoms and mediator release after continuous pollen exposure in an environmental challenge chamber.  
Okuma Y, Okamoto Y, Yonekura S, Iinuma T, Sakurai T, Hamasaki S, Ohki Y, Yamamoto H, Sakurai D.
Ann Allergy Asthma Immunol 2016 Jun 1;
Click to view abstract

Cross-reactive antigens for natural IgE antibodies: allergens with the potential to transform a dormant to an active allergic response?  
Baldo BA.
Clin Exp Allergy 2012 Jun;42(6):810-813

Component-resolved diagnosis with commercially available D. pteronyssinus Der p 1, Der p 2 and Der p 10: relevant markers for house dust mite allergy.  
Bronnert M, Mancini J, Birnbaum J, Agabriel C, Liabeuf V, Porri F, Cleach I, Fabre A, Deneux I, Grandne V, Grob JJ, Berbis P, Charpin D, Bongrand P, Vitte J.
Clin Exp Allergy 2012 Sep;42(9):1406-1415

The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity.  
Blank S, Bantleon FI, McIntyre M, Ollert M, Spillner E.
Clin Exp Allergy 2012 Jun;42(6):976-985

Carrier-bound Alt a 1 peptides without allergenic activity for vaccination against Alternaria alternata allergy.  
Twaroch TE, Focke M, Fleischmann K, Balic N, Lupinek C, Blatt K, Ferrara R, Mari A, Ebner C, Valent P, Spitzauer S, Swoboda I, Valenta R.
Clin Exp Allergy 2012 Jun;42(6):966-975

What do we mean by oral tolerance?  
Anagnostou K, Clark A.
Clin Exp Allergy 2016 Jun;46(6):782-784

Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort.  
Venter C, Maslin K, Arshad SH, Patil V, Grundy J, Glasbey G, Twiselton R, Dean T.
Clin Transl Allergy 2016;622
Click to view abstract

Current challenges facing the assessment of the allergenic capacity of food allergens in animal models.  
Bogh KL, van BJ, Glogowski R, Lopez-Exposito I, Bouchaud G, Blanchard C, Bodinier M, Smit J, Pieters R, Bastiaan-Net S, de WN, Untersmayr E, del-Patient K, Knippels L, Epstein MM, Noti M, .
Clin Transl Allergy 2016;621
Click to view abstract

Nutritional adequacy of a cows' milk exclusion diet in infancy.  
Maslin K, Oliver EM, Scally KS, Atkinson J, Foote K, Venter C, Roberts G, Grimshaw KE.
Clin Transl Allergy 2016;620
Click to view abstract

Incidence and risk factors for food hypersensitivity in UK infants: results from a birth cohort study.  
Grimshaw KE, Bryant T, Oliver EM, Martin J, Maskell J, Kemp T, Clare Mills EN, Foote KD, Margetts BM, Beyer K, Roberts G.
Clin Transl Allergy 2015;61
Click to view abstract

Diagnoses and management of drug hypersensitivity and anaphylaxis in cancer and chronic inflammatory diseases: reactions to taxanes and monoclonal antibodies.  
Bonamichi-Santos R, Castells M.
Clin Rev Allergy Immunol 2016 Jun 8;

Transglutaminase 2 and transglutaminase 2 autoantibodies in celiac disease: a review.  
Rauhavirta T, Hietikko M, Salmi T, Lindfors K.
Clin Rev Allergy Immunol 2016 Jun 4;
Click to view abstract

Indoor Allergens and Allergic Respiratory Disease.  
Pomes A, Chapman MD, Wunschmann S.
Curr Allergy Asthma Rep 2016 Jun;16(6):43
Click to view abstract

Doctor, my child is bullied: food allergy management in schools.  
Egan M, Sicherer S.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):291-296
Click to view abstract

Food allergy quality of life and living with food allergy.  
Greenhawt M.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):284-290
Click to view abstract

Are genetic tests informative in predicting food allergy?  
Li J, Maggadottir SM, Hakonarson H.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):257-264
Click to view abstract

Doctor, can we prevent food allergy and eczema in our baby?  
Waserman S.
Curr Opin Allergy Clin Immunol 2016 Jun;16(3):265-271
Click to view abstract

Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals.  
Subramaniam S, Aslam A, Misbah SA, Salio M, Cerundolo V, Moody DB, Ogg G.
Eur J Immunol 2016 Jan;46(1):242-252
Click to view abstract

The public health issue of allergic contact dermatitis. [German]  
Schnuch A, Mahler V.
Hautarzt 2015 Sep;66(9):644-645

Multiple contact sensitization. [German]  
Schwitulla J, Uter W.
Hautarzt 2015 Sep;66(9):680-685
Click to view abstract

Contact allergies in the elderly. [German]  
Mahler V.
Hautarzt 2015 Sep;66(9):665-673
Click to view abstract

Diagnostic workup of fragrance allergy. [German]  
Geier J, Uter W.
Hautarzt 2015 Sep;66(9):674-679
Click to view abstract

Contact allergies in the German workforce : Data of the IVDK network from 2003-2013. [German]  
Bauer A, Geier J, Mahler V, Uter W.
Hautarzt 2015 Sep;66(9):652-664
Click to view abstract

Identification and characterization of IgE-Binding tropomyosins in Aedes aegypti.  
Cantillo JF, Puerta L, Lafosse-Marin S, Subiza JL, Caraballo L, Fernandez-Caldas E.
Int Arch Allergy Immunol 2016 Jun 30;170(1):46-56
Click to view abstract

Increased pain and muscle glutamate concentration after single ingestion of monosodium glutamate by myofascial temporomandibular disorders patients.  
Shimada A,, Castrillon EE,, Baad-Hansen L,, Ghafouri B, Gerdle B, Wåhlén K, Ernberg M,, Cairns BE, Svensson P,.
Miscellaneous Eur J Pain 2016 Apr 18.
Abstract

Anaphylactic reaction after ongoing exposure to hair glue: a novel case report.  
Burla MJ, Brody AM, Welch RD, Favot MJ.
Miscellaneous J Emerg Med 2015 Jan;48(1):e5-7.
Abstract

A retrospect study into the utility of allergen components in walnut allergy.  
Mew R, Toit GD, Borres M, Sjolander S.
Pediatr Allergy Immunol 2016 Jun 24;
Click to view abstract

Detection of major food allergens in amniotic fluid: initial allergenic encounter during pregnancy.  
Pastor-Vargas C, Maroto AS, az-Perales A, Villalba M, Esteban V, Ruiz-Ramos M, Rodriguez de AM, Vivanco F, Cuesta-Herranz J.
Pediatr Allergy Immunol 2016 Jun 24;
Click to view abstract

The proportion of local allergic rhinitis to Dermatophagoides pteronyssinus in children.  
Buntarickpornpan P, Veskitkul J, Pacharn P, Visitsunthorn N, Vichyanond P, Tantilipikorn P, Jirapongsananuruk O.
Pediatr Allergy Immunol 2016 Jun 11;
Click to view abstract

Fel d 1 synthetic peptides (Cat-PAD) - good news for cat owners with children?  
Pfaar O, Klimek L, Varga EM.
Pediatr Allergy Immunol 2016 Jun 11;
Click to view abstract

Food protein-induced enterocolitis syndrome in two exclusively breastfed infants.  
Kaya A, Toyran M, Civelek E, Misirlioglu ED, Kirsaclioglu CT, Kocabas CN.
Pediatr Allergy Immunol 2016 Jun 11;
Click to view abstract

A comparative analysis between antibiotic- and nonantibiotic-associated delayed cutaneous adverse drug reactions.  
Trubiano JA, Aung AK, Nguyen M, Fehily SR, Graudins L, Cleland H, Padiglione A, Peleg AY.
J Allergy Clin Immunol Pract 2016 Jun 7;
Click to view abstract

Cefazolin Hypersensitivity: Toward Optimized Diagnosis.  
Uyttebroek AP, Decuyper II, Bridts CH, Romano A, Hagendorens MM, Ebo DG, Sabato V.
J Allergy Clin Immunol Pract 2016 Jun 14;
Click to view abstract

Drug hypersensitivity workup for suspected pristinamycin drug hypersensitivity.  
Schrijvers R, Lagara K, Breynaert C, Demoly P, Chiriac AM.
J Allergy Clin Immunol Pract 2016 Jun 8;

Adult but no pediatric anaphylaxis-related deaths in the Finnish population from 1996 to 2013.  
Kivisto JE, Dunder T, Protudjer JL, Karjalainen J, Huhtala H, Makela MJ.
J Allergy Clin Immunol 2016 Jun 21;

Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition.  
Feeney M, Du TG, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G.
J Allergy Clin Immunol 2016 Jun 8;
Click to view abstract

The discovery of IgE.  
Johansson SG.
J Allergy Clin Immunol 2016 Jun;137(6):1671-1673
Click to view abstract

IgE in the diagnosis and treatment of allergic disease.  
Platts-Mills TA, Schuyler AJ, Erwin EA, Commins SP, Woodfolk JA.
J Allergy Clin Immunol 2016 Jun;137(6):1662-1670
Click to view abstract

Role of IgE in autoimmunity.  
Sanjuan MA, Sagar D, Kolbeck R.
J Allergy Clin Immunol 2016 Jun;137(6):1651-1661
Click to view abstract

Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases.  
Oettgen HC.
J Allergy Clin Immunol 2016 Jun;137(6):1631-1645
Click to view abstract

Sensitization of a child to Cyanobacteria after recreational swimming in a lake.  
Geh EN, de la Cruz AA, Ghosh D, Stelma G, Bernstein JA.
J Allergy Clin Immunol 2016 Jun;137(6):1902-1904

Clinical practice guidelines for diagnosis and management of hypersensitivity reactions to contrast media.  
Rosado IA, Dona D, Cabanas MR, Moya Quesada MC, Garcia-Aviles C, Garcia N, Martinez Tadeo JI, Mielgo BR, Ortega-Rodriguez N, Padial Vilchez MA, Sanchez-Morillas L, Vila AC, Moreno RE, T.
J Investig Allergol Clin Immunol 2016 Jun;26(3):144-155
Click to view abstract

The Smartphone: a novel diagnostic tool in pollen allergy?  
Bianchi A, Tsilochristou O, Gabrielli F, Tripodi S, Matricardi PM.
J Investig Allergol Clin Immunol 2016 Jun;26(3):204-207

Anaphylactic shock caused by a hidden allergen in blood sausage.  
Canabal J, Caballero T, Caminoa M, Fiandor A, Quirce S, Cabanas R.
J Investig Allergol Clin Immunol 2016 Jun;26(3):200-201

Nonoccupational airborne-induced anaphylaxis caused by Anisakis simplex.  
Barbarroja-Escudero J, Sanchez-Gonzalez MJ, ntolin-Amerigo D, Rodriguez-Rodriguez M, varez-Mon M.
J Investig Allergol Clin Immunol 2016 Jun;26(3):196-197

Pollen Counts Influence Web Searches for Asthma and Rhinitis.  
Gaspar MJ, Carreiro MP, Belo J, Alves C, Paiva M, Caeiro E, Leiria-Pinto P.
J Investig Allergol Clin Immunol 2016 Jun;26(3):192-194

Does the profile of sensitization to grass pollen allergens have clinical relevance?  
Palao-Ocharan P, Dominguez-Ortega J, Barranco P, az-Almiron M, Quirce S.
J Investig Allergol Clin Immunol 2016 Jun;26(3):188-189

Clinical performance of commercial ISAC 112 Allergen microarray versus noncommercial RIRAAF platform for the diagnosis of plant food and olive pollen allergies.  
Martinez-Aranguren R, Martinez-Botas J, az-Perales A, Villalba M, de la HB, Gomez F, Bartra J, Blanca-Lopez N, Alvarado MI, Moya C, Feo BF, Alonso MD, Gonzalez-Mancebo E, Terrados S, Gar.
J Investig Allergol Clin Immunol 2016 Jun;26(3):185-187

Top 10 food allergy myths.  
Nickolls C, Campbell DE.
J Paediatr Child Health 2015 Sep;51(9):852-856


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