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 Allergy Advisor Digest - March 2014
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Read Identification and characterization of a pan-allergen profilin, a major allergen from Caryota mitis pollen.
Read Unusual shift from IgE-mediated milk allergy to food protein-induced enterocolitis syndrome.
Read Contact urticaria to Cannabis sativa due to a lipid transfer protein (LTP).
Read Establishing a cut-off for the serum levels of specific IgE to milk and its components for cow's milk allergy: Results from a specific population.
Read Anaphylaxis caused by skin prick testing with inhalant allergens.
Read Legumes steam allergy in childhood: Update of the reported cases.
Read Profilin sensitisation in a Mediterranean population.
Read Prevalence of parent-reported immediate hypersensitivity food allergy in Chilean school-aged children.
Read IgE-mediated reaction induced by arugula (Eruca sativa) ingestion
Read Rosemary (Rosmarinus officinalis) as cause of contact dermatitis.
Read Heat immersion therapy-A new approach for contact dermatitis to propolis?
Read Anaphylactic reaction to bell pepper in a patient with a latex-fruit syndrome.
Read Utility of opium seed extract tests in preventing hypersensitivity reactions during surgery.
Read Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.
Read Food-dependent exercise-induced anaphylaxis to nectarine
Read Allergy to goat and sheep cheese with tolerance to cow's milk and its derivatives.
Read Risk of adverse IgE-mediate reaction at the first egg ingestion in children with atopic dermatitis.
Read Cold-induced urticaria with systemic reactions after hymenoptera sting lasting for 10 years.
Read Milk-induced wheezing in children with asthma.
Read Imunoreactivity to broad bean proteins in a Moroccan population.
Read Agreement between the skin prick test and specific serum IgE for egg white and cow's milk allergens in young infant with atopic dermatitis.
Read Allergy to illicit drugs and narcotics.
Read Glucoamylase is a major allergen of Schizophyllum commune.
Read Improved prediction of clinical allergic reaction to peanut challenge in children.
Read Reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy.
Read Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food.
Read Present state of Japanese cedar pollinosis: Japan's national affliction.
Read Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1,3-galactose.
Read Structural biology of mite allergens.
Read Diagnosis of Chenopodium album allergy with a cocktail of recombinant allergens as a tool for component-resolved diagnosis.
Read Long-term prognostic value of component-resolved diagnosis in infants and toddlers with peanut allergy.

Abstracts shared in March 2014 Advisor Digest Newsletter

Read Pomegranate anaphylaxis due to cross-reactivity with Peach LTP (Pru p 3).
Read Coconut anaphylaxis: Case report and review.
Read Allergy to quince.
Read Unexpected cross-reactivity in a cat-allergy patient - at the circus.
Read Allergy to all mammalian Bovidae proteins but cow's milk in a child.
Read A neglected cause for chronic spontaneous urticaria in children: Helicobacter pylori.
Read Oral mite anaphylaxis caused by mite-contaminated okonomiyaki/ pancake-mix in Japan
Read Usefulness of nBos d 4, 5 and nBos d 8 specific IgE antibodies in cow's milk allergic children.
Read Allergen microarray detects high prevalence of asymptomatic IgE sensitizations to tropical pollen-derived carbohydrates.
Read Allergy to goat/sheep’s milk with good tolerance to cow’s milk but not to cow’s milk cheese: molecular basis of reactivity
Read Is the determination of specific IgE against components using ISAC 112 a reproducible technique?

Allergy and Intolerance Abstracts
Identification and characterization of a pan-allergen profilin, a major allergen from Caryota mitis pollen.
Caryota mitis (Burmese Fishtail Palm) is a common plant in tropical and subtropical areas. It produces larger amount of pollen, which has great potential for allergenicity in the pollination season. This study aimed to identify the components of Caryota mitis pollen contributing to human allergic diseases. Sera from 20 patients with a positive skin prick test to Caryota mitis pollen crude extract (CmPCE) were collected. Sixteen out of 20 collected serum samples reacted to a 14 kDa protein fractioned from CmPCE; this 14 kDa antigen also had positive reactions to CmPCE in an ELISA assay. 12 samples from 20 collected serums positively reacted to recombinant CmProfilin (rCmProfilin). The 14 kDa protein from the CmPCE was identified as the major allergic component of CmPCE.

Identification and characterization of a pan-allergen profilin, a major allergen from Caryota mitis pollen.  
Liu X, Xiao X, Xia L, Yang PC, Liu Z, Li L.
Asian Pac J Allergy Immunol 2014 Mar;32(1):39-45

Click to view abstract

Index
Allergy and Intolerance Abstracts
Unusual shift from IgE-mediated milk allergy to food protein-induced enterocolitis syndrome.
Food protein-induced enterocolitis syndrome (FPIES) is a potentially severe non-IgE-mediated food allergy usually caused by cow's milk or soy, and more rarely by solid foods such as rice, oats, barley, chicken, turkey, egg white, green peas and peanuts. In children with FPIES, the presence of specific IgE antibodies to the causative food, either at presentation or during follow-up, defines an 'atypical form' of FPIES characterized by a lesser probability of developing tolerance and a potential progression to typical IgE-mediated hypersensitivity. Although it is uncommon, the shift from non-IgE-mediated milk-protein induced enterocolitis syndrome to IgE-mediated milk allergy has recently been described. We report the first case, to our knowledge, of a shift from IgE-mediated cow's milk allergy to pure non-IgE-mediated FPIES, in a 4-month-old male infant.

Unusual shift from IgE-mediated milk allergy to food protein-induced enterocolitis syndrome.  
Banzato C, Piacentini GL, Comberiati P, Mazzei F, Boner AL, Peroni DG.
Eur Ann Allergy Clin Immunol 2013 Dec;45(6):209-211

Click to view abstract

Index
Allergy and Intolerance Abstracts
Contact urticaria to Cannabis sativa due to a lipid transfer protein (LTP).
This study reports contact urticaria to Cannabis sativa due to a lipid transfer protein (LTP). A 30-year-old man without atopy history began to work in C. sativa harvesting for therapeutic use. After two months he developed several episodes of wheals and pruritus immediately after the contact of the skin with the leaves while collecting the plant. The symptoms disappeared spontaneously in less than an hour. He previously consumed C. sativa recreationally (smoked) with good tolerance. Prick-by-prick test was carried out with dried and fresh C. sativa leaf obtaining positive results. Patch tests with dry and fresh leaf were negative. Total IgE was 241 kU/L. Two antibody-binding bands with the same molecular mass, approximately 14 kDa and 12 kDa, were seen on immunoblot and identified as lipid transfer proteins.

Contact urticaria to Cannabis sativa due to a lipid transfer protein (LTP).  
Rojas Perez-Ezquerra P, Sanchez-Morillas L, vila-Ferandez G, Ruiz-Hornillos FJ, Carrasco G, Herranz MM, Laguna Martinez JJ, Bartolome B.
Allergol Immunopathol (Madr ) 2014 Mar 20;

Index
Allergy and Intolerance Abstracts
Establishing a cut-off for the serum levels of specific IgE to milk and its components for cow's milk allergy: Results from a specific population.
The aim of this study was to compare discriminating concentration of a cow's milk specific IgE and its fractions (alpha-lactoalbumin, beta-lactoglobulin, casein) in children for the CMA diagnosis. The study included 123 patients median age at diagnosis=1.91 years, (3.5m to 13.21y) Considering 98% specificity, cut-off points were: 3.06kU/L for cow's milk, 2.06kU/L for alpha-lactalbumin, 1.85kU/L for beta-lactoglobulin and 1.47kU/L for casein. This study showed that the cut-off point detected for whole cow's milk revealed a better discriminatory capacity for CMA diagnosis without the necessity of the milk components testing.

Establishing a cut-off for the serum levels of specific IgE to milk and its components for cow's milk allergy: Results from a specific population.  
Castro AP, Pastorino AC, Gushken AK, Kokron CM, Filho UD, Jacob CM.
Allergol Immunopathol (Madr ) 2014 Jan 29;

Index
Allergy and Intolerance Abstracts
Anaphylaxis caused by skin prick testing with inhalant allergens.
A nine-year-old boy had SPT performed with commercial extracts of Dermatophagoides pteronyssinus, D. farinae, grasses, tree pollens, cereals, wild grass pollens, animal danders, molds and histamine. Five minutes after the SPT, the patient became pale, urticarial lesions began on his face, cough and respiratory distress started. SPT was strongly positive with pseudopodia for house dust mites, with whealing and erythema greater than the histamine reaction sizes of erythema/whealing. Total IgE level was 310 kU/L, speci?c IgE for D. pteronyssinus was 90 kU/L and D. farinae 92 kU/L.

Are skin prick tests really safe? A case of anaphylaxis caused by skin prick testing with inhalant allergens.  
Babayigit HA, Cipe F, Aydogmus C.
Allergol Immunopathol (Madr ) 2014 Jan 29;

Index
Allergy and Intolerance Abstracts
Legumes steam allergy in childhood: Update of the reported cases.
In literature there are numerous descriptions of adverse reactions after ingestion of uncooked and cooked legumes. Nevertheless, cases of allergic reactions induced by inhaling vapours from cooking legumes have rarely been described. Herein the authors report an update of the literature data on allergic reactions caused by legume steam inhalation, underlying the possible pathogenic mechanism of these atopic events and the knowledge of literature data in paediatric age. The importance of this review is the focus on the clinical aspects concerning legume vapour allergy, referring to literature data in childhood

Legumes steam allergy in childhood: Update of the reported cases.  
Vitaliti G, Pavone P, Spataro G, Giunta L, Guglielmo F, Falsaperla R.
Allergol Immunopathol (Madr ) 2014 Jan 7;

Index
Allergy and Intolerance Abstracts
Profilin sensitisation in a Mediterranean population.
The objective of this study was to investigate the profile of sensitisation to profilins and to correlate it with sensitisation to foods and pollens. Six hundred and fifty-four consecutive patients were skin-prick tested with a battery of common allergens including pollens, epithelia, mites and moulds and profilin and divided into three groups depending on their sensitisation profile (non-atopic, atopic with pollinosis and atopic without pollinosis). Patients with symptoms were challenged and diagnosed with the offending food extracts. Profilin sensitisation was identified and analysed in detail. The prevalence of profilin sensitisation was estimated at 2.9% in patients suffering respiratory allergy, 4.2% in atopic patients, and 5.9% in pollen-sensitised individuals. Positive association was observed between pollen (except Cupressus and olive) and profilin but not with moulds, mites or epithelia. With respect to foods, positive association was only observed between profilin and melon sensitisation. Lastly, in terms of symptoms, positive association was only observed between profilin sensitisation and OAS.

Profilin sensitisation in a Mediterranean population.  
Huertas AJ, Carreno A, Merida C, Pajaron-Fernandez MJ, Ramirez-Hernandez M, Carnes J.
Allergol Immunopathol (Madr ) 2014 Jan 7;

Index
Allergy and Intolerance Abstracts
Prevalence of parent-reported immediate hypersensitivity food allergy in Chilean school-aged children.
In this Chilean study, up to 5.5% of school-aged Chilean children may suffer from FA, most frequently to walnut and peanut. Foods reported to frequently cause food allergy included walnut, peanut, egg, chocolate, avocado, and banana. The parents of children with FA did not report anaphylaxis, but 48% had history compatible with anaphylaxis.

Prevalence of parent-reported immediate hypersensitivity food allergy in Chilean school-aged children.  
Hoyos-Bachiloglu R, Ivanovic-Zuvic D, Alvarez J, Linn K, Thone N, de Los Angeles PM, Borzutzky A.
Allergol Immunopathol (Madr ) 2014 Jan 2;

Index
Allergy and Intolerance Abstracts
IgE-mediated reaction induced by arugula (Eruca sativa) ingestion
A 32-year-old housewife reported urticaria to the trunk a few minutes after ingestion of pizza with raw arugula leaves. Prick by prick test with raw arugula was positive. Oral challenge tests was refused. Immunoblotting did not show IgE reactivity to proteins in the cooked extract, but reactive bands of about 60 - 67 kDa was shown in the raw arugula extract. The patient did not report reactions after ingestion of other Brassicacea family members, i.e., cooked turnips and cauli?ower, and she did not remember having eaten radish and/or cabbage. Prick to prick tests with other cooked and raw Brassicacea showed positivity only for raw foods.

IgE-mediated reaction induced by arugula (Eruca sativa) ingestion compared with a spectrum of Brassicaceae proteins.  
Damiani E, Aloia AM, Priore MG, Pastore A, Lovecchio A, Errico M, Ferrannini A, Macchia L.
Allergol Immunopathol (Madr ) 2013 Jul 4;

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Allergy and Intolerance Abstracts
Rosemary (Rosmarinus officinalis) as cause of contact dermatitis.
Rosmarinus officinalis L. (rosemary) is used worldwide as a spice and flavouring agent, as a preservative and for medicinal and cosmetic purposes. The present article aims to reviews the scientific literature reporting cases of contact dermatitis caused by the use of R. officinalis as a raw material or as herbal preparations. The published case reports show that both rosemary extracts and raw material can be responsible for allergic contact dermatitis. Two cases of contact dermatitis caused by cross-reactivity between rosemary and thyme were also noted. The diterpene carnosol, a chemical constituent of this plant, has been imputed as a common cause for this reaction. The incidence of contact dermatitis caused by rosemary is not common, but it could be more frequent with respect to the supposed occurrence. Contact dermatitis caused by rosemary may be more common but is misdiagnosed.

Rosmarinus officinalis L. as cause of contact dermatitis.  
Miroddi M, Calapai G, Isola S, Minciullo PL, Gangemi S.
Allergol Immunopathol (Madr ) 2013 Jul 1;

Index
Allergy and Intolerance Abstracts
Heat immersion therapy-A new approach for contact dermatitis to propolis?
A 62-year-old beekeeper wrote to the author stating that he had suffered from propolis contact allergy since 1985. He wore cotton gloves as a protective measure. Since contact with propolis could not be avoided completely, he frequently suffered from contact allergy with itchy rashes and ablation of areas of skin. He wrote that he started to immerse his hands in water with a temperature of about 50 ?C, which intensified itching at the beginning but gave relief after a few minutes. He reported that he repeated this five to six times if necessary. Most importantly he wrote

that the itching was gone after the procedure and that all skin affections did not occur. He was also able to stop taking corticoid containing creams which he had previously required.

Heat immersion therapy-A new approach for contact dermatitis to propolis?  
Munstedt K.
Allergol Immunopathol (Madr ) 2013 May 29;

Index
Allergy and Intolerance Abstracts
Anaphylactic reaction to bell pepper in a patient with a latex-fruit syndrome.
A 33-year-old woman experienced three episodes of facial, palpebral and oropharyngeal angio-oedema with difficulty in breathing and swallowing and generalised urticaria 10 min after eating raw green pepper. She had been previously diagnosed with rhinoconjunctivitis and moderate persistent asthma and latex allergy. She had presented with four similar, one after eating

paprika (dried bell-pepper fruit) seasoned octopus, another one after eating chestnuts, walnuts and a fig and two others with a banana and an avocado. Before the first clinical episode with green bell pepper she suffered from pruritus and angio-oedema in hands after skin contact

with green and red bell peppers, but she ate bell peppers without reaction. Skin prick tests were positive only for cat and dog epithelia, latex and paprika. Prick-by-prick tests performed with green and red fresh peppers were both positive. Total serum IgE was 282 IU/mL and specific serum IgE positive for latex (1.82 kU/l) and banana (0.44 kU/l) but negative for chestnut and paprika. She presented a very weak positive result for chestnut chitinase (Cas s 5) and a moderate/high positive result for the cross-reactive allergen hevein (Hev b 6). One of the bands present in the immunoblotting is near to 34 kDa, which is the molecular weight of Cas s 5. This could perhaps explain the latex-fruit syndrome suffered by this patient.

Anaphylactic reaction to bell pepper (Capsicum annuum) in a patient with a latex-fruit syndrome.  
Garcia-Menaya JM, Cordobes-Duran C, Bobadilla-Gonzalez P, Ledesma A, Perez-Rangel I, Sanchez-Vega S, Zambonino MA, Corrales-Vargas S.
Allergol Immunopathol (Madr ) 2013 Mar 25;

Index
Allergy and Intolerance Abstracts
Utility of opium seed extract tests in preventing hypersensitivity reactions during surgery.
Anaphylaxis during anaesthesia is fatal in 3-9% of patients and analgesics, including opioids, and is the second most common medicament-related cause, although the prevalence is underestimated. This study evaluated the diagnostic accuracy of specific antibodies to morphine, codeine, rocuronium and oil body and aqueous fractions of Papaver somniferum seeds in the diagnosis and prevention of allergy to opioids, and concludes that although sensitivity to opioids and intraoperative anaphylaxis can be diagnosed by routine tests, IgE and skin tests for the oil body fraction of P. somniferum had the highest sensitivity for sensitisation to opioids.

Utility of opium seed extract tests in preventing hypersensitivity reactions during surgery.  
Armentia A, Pineda F, Palacios R, Martin-Gil FJ, Miguel AS, Arenal JJ, Tejedor J, Tef BM.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):56-63

Index
Allergy and Intolerance Abstracts
Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.
Chlorhexidine is widely used as an antiseptic agent. It is a potentially allergenic substance that can cause severe hypersensitivity reactions. This study describes six patients who had anaphylactic reactions attributed to chlorhexidine during surgery. These patients were exposed to chlorhexidine in gels, swabs and catheters. The authors conclude that immediate hypersensitivity to chlorhexidine appears to be common but underreported in the UK.

Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.  
Nakonechna A, Dore P, Dixon T, Khan S, Deacock S, Holding S, Abuzakouk M.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):44-49

Index
Allergy and Intolerance Abstracts
Food-dependent exercise-induced anaphylaxis to nectarine
Food-dependent exercise-induced anaphylaxis (FDEIA) by nectarine in a 14-year-old boy, with weakly positive nectarine prick-by-prick and negative specific IgE to Pru p 3. He ate two nectarines with peel and after a few minutes he started running again and immediately experienced bilateral ocular oedema, nasal obstruction and ocular and nasal itching. Before this episode, he regularly ate nectarines with peel. Skin prick tests with commercial peach extract and prick-by-prick (PP) with peach (pulp and peel) produced a 2mm wheal. Peach specific IgE was 0.10 kUA/L. OFC followed by exercise test was positive.

Food-dependent exercise-induced anaphylaxis (FDEIA) by nectarine in a paediatric patient with weakly positive nectarine prick-by-prick and negative specific IgE to Pru p 3.  
Miceli SS, Monaco S, Giorgio V, Calvani M, Mistrello G, Onesimo R.
Allergol Immunopathol (Madr ) 2013 May;41(3):201-203

Index
Allergy and Intolerance Abstracts
Allergy to goat and sheep cheese with tolerance to cow's milk and its derivatives.
Two adult and three paediatric patients had allergic reactions after cheese ingestion and subsequently tolerated cow's milk derivatives. This study determined possible cross-reactivity between different types of cheese. Skin tests were positive for casein in the patients. The prick-prick tests were positive for the three cheeses in patients 1 and 4, for goat and sheep cheese in patients 2 and 3, and for sheep cheese in patient 5. The specific IgE test was positive in patients 1, 3 and 4 for goat and sheep cheese, and negative in patients 2 and 5. Serum 3 and 4 clearly recognised goat and sheep cheese extracts. Goat casein was almost completely inhibited with sheep casein and partially inhibited with goat and sheep serum proteins, while there was no inhibition with cow cheese. Sheep casein was totally inhibited with sheep serum proteins. Sheep casein was inhibited with goat and cow caseins, suggesting cross-reactivity among the three types of cheese. Sensitisation to goat and sheep cheese was demonstrated in two patients, and only to sheep cheese in another two of the studied patients.

Allergy to goat and sheep cheese with tolerance to cow's milk and its derivatives.  
Vinas M, Carnes J, Lopez-Matas MA, Hernandez N, Castillo MJ, Ibero M.
Allergol Immunopathol (Madr ) 2012 Dec 17;

Index
Allergy and Intolerance Abstracts
Risk of adverse IgE-mediate reaction at the first egg ingestion in children with atopic dermatitis.
This study concludes that a child with AD has a Relative Risk of sensitisation to egg six times higher than a child without AD, before the first known ingestion. We propose to test sensitisation to egg in every child with AD who has never eaten egg, and to perform OFC in those with positive SPT in hospital setting.

Risk of adverse IgE-mediate reaction at the first egg ingestion in children with atopic dermatitis. Results of a case-control study.  
Miceli SS, Monaco S, Giorgio V, Calvani M, Tripodi S, Onesimo R.
Allergol Immunopathol (Madr ) 2012 Dec 17;

Index
Allergy and Intolerance Abstracts
Cold-induced urticaria with systemic reactions after hymenoptera sting lasting for 10 years.
A 20-year-old man with complaints of intense pruritus, generalised erythema and oedema on the trunk, face and extremities after exposure to cold. He had experienced the same symptoms on cold rainy days. The patient reported that all his cold-related complaints had begun 10 years ago shortly after a common wasp sting on his head, which was limited to mild local reaction. Two years after the wasp sting, he experienced a mild anaphylactic reaction (chest tightness, nausea, dizziness, abdominal pain) while standing in a cold river for fishing. The cold contact stimulation test (CST) with an ice cube in a plastic bag (3, 5 and 8 min) was positive only at 8 min. Bee venom-specific IgE were positive for Apis Mellifera (1.32 kUA/L), and Vespula Spp (1.08 kUA/L).

Cold-induced urticaria with systemic reactions after hymenoptera sting lasting for 10 years.  
Kutlu A, Aydin E, Goker K, Karabacak E, Ozturk S.
Allergol Immunopathol (Madr ) 2013 Jul;41(4):283-284

Index
Allergy and Intolerance Abstracts
Milk-induced wheezing in children with asthma.
Food allergy has been gaining increasing attention, mostly as causing gastrointestinal and cutaneous reactions. Its role in asthma seems to be under-recognised. This study's aim was to explore the frequency of involvement of cow's milk in childhood asthma. 32 children (5 months to 11 years) with asthma and a suspected history of cow's milk allergy were studied. Reactions to milk challenge occurred in 12 (37.5%) including wheezing in 5 (41.7%, or 15.6% of the whole group). Challenge was positive in 33.3% of subjects who had a positive SPT, and SPT was positive in 50% of challenge-positive subjects. Challenge was positive in 26.7% of sIgE-positive subjects, and sIgE was positive in 33.3% of challenge positive subjects. Skin or serum testing with individual protein fractions did not seem to add significant advantage over testing with WCM alone.

Milk-induced wheezing in children with asthma.  
Murray MG, Kanuga J, Yee E, Bahna SL.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):310-314

Index
Allergy and Intolerance Abstracts
Imunoreactivity to broad bean proteins in a Moroccan population.
This study assessed the sensitivity profile of the population of Fez and Casablanca in Morocco to dry broad bean (Vicia faba). Sera samples from 146 patients with atopic hypersensitivity evaluated for specific IgE levels to native and processed broad bean proteins by ELISA. High IgE levels to BBP were found; 79.3% of children and 80.4% of adults were positive. The heat treatment (70 degrees C during 60min) of dry beans proteins showed slight reduction in recognition of antigens. This study demonstrates a high sensitivity of a Moroccan population to broad bean proteins which was resistant to heat and digestion by pepsin.

Modulation of IgE immunoreactivity to broad bean proteins after food processing in a Moroccan population.  
Bousfiha A, Aarab L.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):29-34

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Allergy and Intolerance Abstracts
Agreement between the skin prick test and specific serum IgE for egg white and cow's milk allergens in young infant with atopic dermatitis.
The skin prick test (SPT) for detecting atopic sensitization is not preferred in young infants with atopic dermatitis (AD) because of concerns about poor skin reactivity. This study aimed to evaluate whether the results of SPT agreed well with those of specific serum immunoglobulin E (sIgE) antibody test in young infants with AD. This study included 2,077 eligible infants (age, <12 months) with AD who were tested by either SPT or sIgE. The study concludes that the results of SPT agreed well with those of sIgE. This finding provides a rationale for using SPT, and suggests that SPT can be used along with sIgE to detect food sensitization in young infants with AD.

Agreement between the skin prick test and specific serum IgE for egg white and cow's milk allergens in young infant with atopic dermatitis.  
Yang HJ, Park MJ, Youn SY, Yoo S, Min TK, Jeon YH, Lee HW, Lee JS, Pyun BY.
Allergol Int 2014 Mar 25;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Allergy to illicit drugs and narcotics.
Despite their frequent use, allergy to illicit drugs and narcotics is rarely reported in literature. This article is a review of the different classes of drugs of abuse that might be involved in allergies: central nervous system (CNS) depressants (such as cannabis, opioids and kava), CNS stimulants (cocaine, amphetamines, khat and ephedra) and hallucinogens such as ketamine and nutmeg. For various reasons, correct diagnosis of most of these drug allergies is not straightforward. For example, the native plant material applied for skin testing and sIgE antibody tests might harbour irrelevant IgE-binding structures that hamper correct diagnosis. Diagnosis might also be hampered due to uncertainties associated with the non-specific histamine releasing characteristics of some compounds and absence of validated sIgE tests.

Allergy to illicit drugs and narcotics.  
Swerts S, Van GA, Leysen J, Faber M, Sabato V, Bridts CH, Jorens PG, De Clerck LS, Ebo DG.
Clin Exp Allergy 2014 Mar;44(3):307-318

Click to view abstract

Index
Allergy and Intolerance Abstracts
Glucoamylase is a major allergen of Schizophyllum commune.
Schizophyllum commune is one of the causative agents of basidiomycosis including disorders such as allergic bronchopulmonary mycosis, allergic fungal sinusitis, and mucoid impaction of bronchi, the incidence of those of which has been increasing. No specific antigens of S. commune have been identified to enable serodiagnosis of the disease. This study attempted to identify a major antigen of S. commune to establish a reliable serodiagnostic method. A protein identified as a major antigen of S. commune was identified and named Sch c 1; it was a homolog of glucoamylase. The IgG and IgE titres against Sch c 1 in patient sera were significantly higher than those in healthy volunteer sera.

Glucoamylase is a major allergen of Schizophyllum commune.  
Toyotome T, Satoh M, Yahiro M, Watanabe A, Nomura F, Kamei K.
Clin Exp Allergy 2014 Mar;44(3):450-457

Index
Allergy and Intolerance Abstracts
Improved prediction of clinical allergic reaction to peanut challenge in children.
Studies of childhood peanut allergy demonstrate serum-specific IgE levels against the peanut allergen Ara h2 may help predict a clinical reaction at food challenge. This study assessed the validity of serum-specific Ara h2 IgE measured prospectively to diagnose peanut allergy and explore the utility of FeNO as a non-invasive screening tool for childhood food challenge. 53 children scheduled for an open-labelled peanut food challenge were evaluated. Ara h2-specific IgE and FeNO each showed improved diagnostic accuracy when compared to SPT. AUC for Ara h2 sIgE was 0.84, AUC for FeNO 0.83 and combined AUC for SPT, sIgE to Ara h2 and FeNO was 0.96. Prospectively measured Ara h2-specific IgE improves diagnostic accuracy and reduces unsuccessful challenge to peanut. FeNO levels may provide improved diagnostic accuracy in a paediatric population undergoing OFC.

The fraction of exhaled nitric oxide improves prediction of clinical allergic reaction to peanut challenge in children.  
Preece K, Bhatia R, Belcher J, Patchett K, McElduff P, Collison A, Mattes J.
Clin Exp Allergy 2014 Mar;44(3):371-380

Click to view abstract

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Allergy and Intolerance Abstracts
Reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy.
Actinidin, an abundant cysteine protease from kiwifruit, is a specific biomarker of isolated allergy to kiwifruit. This study evaluates the IgE-binding properties of biologically active and thermally inactivated actinidin. Actinidin obtained from kiwifruit extract was capable of inducing positive skin prick test reactions, but the authors failed to detect IgE reactivity of active actinidin in Western blot with patient sera. Thermally inactivated actinidin exhibited IgE reactivity both in vivo and in vitro, indicating that heat processed kiwifruit products may induce clinical reactivity. These findings imply that apart from the allergenic epitopes on its surface, actinidin also contains hidden epitopes inside the protein which become accessible to IgE upon thermal treatment.

Evaluation of IgE reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy.  
Grozdanovic M, Popovic M, Polovic N, Burazer L, Vuckovic O, tanaskovic-Markovic M, Lindner B, Petersen A, Gavrovic-Jankulovic M.
Food Chem Toxicol 2012 Mar;50(3-4):1013-1018

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Allergy and Intolerance Abstracts
Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food.
This study sought to assess the association between IgE-mediated food allergy and EoE in a cohort of children. A total of 1025 subjects had confirmed EoE, and a definitive causal food was identified by biopsy for 425 subjects. Of these 425, 84 had a history of IgE-mediated food allergy to any food (preceding/concurrent with EoE diagnosis); 17 of the 84 subjects outgrew their IgE-mediated food allergy and subsequently developed EoE to the same food. Thus, IgE-mediated food allergy may proceed, and possibly predispose to, the development of EoE, with the pathogenesis of EoE being distinct from that of IgE-mediated food allergy.

Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food.  
Maggadottir SM, Hill DA, Ruymann K, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Chikwava K, Verma R, Liacouras CA, Spergel JM.
J Allergy Clin Immunol 2014 Mar 15;

Index
Allergy and Intolerance Abstracts
Present state of Japanese cedar pollinosis: Japan's national affliction.
Seasonal allergic rhinitis (SAR) caused by Japanese cedar pollen (JCP; ie, sugi-pollinosis) is the most common disease in Japan and has been considered a national affliction. More than one third of all Japanese persons have sugi-pollinosis, and this number has significantly increased in the last 2 decades. In our opinion the reason why sugi-pollinosis became a common disease in the last half century is the increased number of cedar pollens, with global climate change and forest growth caused by the tree-planting program of the Japanese government after World War II playing substantial roles; dust storms containing small particulate matter from China might also contribute to the increased incidence of sugi-pollinosis. To help minimize their symptoms, many Japanese wear facemasks and eyeglasses at all times between February and April to prevent exposure to JCP and aerosol pollutants. Forecasts for JCP levels typically follow the weather forecast in mass media broadcasts, and real-time information regarding JCP levels is also available on the Internet. Because a large amount of JCP is produced over several months, it can induce severe symptoms. Many patients with sugi-pollinosis do not find satisfactory symptom relief with currently available therapies.

Present state of Japanese cedar pollinosis: The national affliction.  
Yamada T, Saito H, Fujieda S.
J Allergy Clin Immunol 2014 Mar;133(3):632-639

Click to view abstract

Index
Allergy and Intolerance Abstracts
Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1,3-galactose.
This study sought to formally document the time course of clinical symptoms after the ingestion of mammalian meat in subjects with IgE to alpha-gal and to monitor ex vivo for the appearance of markers of an allergic reaction. Open food challenges were performed with mammalian meat in 12 subjects with a history of severe urticarial reactions 3 to 6 hours after eating beef, pork, or lamb, as well as in 13 control subjects. Ten of 12 subjects with IgE to alpha-gal had clinical evidence of a reaction during the food challenge. The reactions occurred 3 to 7 hours after the initial ingestion of mammalian meat and ranged from urticaria to anaphylaxis. Tryptase levels were positive in 3 challenges. Basophil activation, as measured by increased expression of CD63, correlated with the appearance of clinical symptoms. In vivo basophil activation during a food challenge occurred in the same time frame as clinical symptoms and likely reflects the appearance of the antigen in the bloodstream.

Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1,3-galactose.  
Commins SP, James HR, Stevens W, Pochan SL, Land MH, King C, Mozzicato S, Platts-Mills TA.
J Allergy Clin Immunol 2014 Mar 19;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Structural biology of mite allergens.
Mite allergens contribute to a significant proportion of human allergic symptoms, including asthma and rhinitis. The development of therapies to treat and prevent these symptoms depends largely on our understanding of the properties of these allergens. Much effort has been devoted to determining the structure and organization of mite allergens, particularly of the house dust mites, toward understanding their activities and how they elicit immunological responses in humans. Here, we review the structural biology of the major allergens from two species of house dust mites, Dermatophagoides farinae and D. pteronyssinus, as well as allergens from a storage mite, Blomia tropicalis. The knowledge gained from the structural biology of these allergens will enable progress in producing novel, more effective treatments for mite allergies based on specific immunotherapy approaches

Structural biology of mite allergens.  
Cui Y.
Mol Biol Rep 2013 Jan;40(1):681-686

Index
Allergy and Intolerance Abstracts
Diagnosis of Chenopodium album allergy with a cocktail of recombinant allergens as a tool for component-resolved diagnosis.
Chenopodium album pollen is one of the main sources of pollen allergy in desert and semi-desert areas and contains three identified allergens, so the aim of this study was the comparison of the diagnostic potential of C. album recombinant allergens in an allergenic cocktail and C. album pollen extract. Diagnostic potential of the allergenic cocktail was investigated in 32 individuals using skin prick test and obtained results were compared with the acquired results from C. album pollen extract. Specific IgE reactivity against the pollen extract and allergenic cocktail was determined by ELISA and western blotting tests. Results showed that 72, 81 and 46% of allergic patients had IgE reactivity to rChe a 1, rChe a 2 and rChe a 3, respectively. Almost all of C. album allergic patients (30/32) had specific IgE against the allergenic cocktail. In addition, there was a high correlation between IgE levels against the allergenic cocktail and IgE levels against the pollen extract. The allergenic cocktail was able to completely inhibit IgE binding to natural Che a 1, Che a 2 and Che a 3 in C. album extract. In addition, positive skin test reactions were seen in allergic patients that tested by the allergenic cocktail. The reliable results obtained from this study confirmed that the allergenic cocktail with high diagnostic potential could be replaced with natural C. album allergen extracts in skin prick test and serologic tests.

Diagnosis of Chenopodium album allergy with a cocktail of recombinant allergens as a tool for component-resolved diagnosis.  
Nouri HR, Sankian M, Vahedi F, Afsharzadeh D, Rouzbeh L, Moghadam M, Varasteh A.
Mol Biol Rep 2012 Mar;39(3):3169-3178

Index
Allergy and Intolerance Abstracts
Long-term prognostic value of component-resolved diagnosis in infants and toddlers with peanut allergy.
While component-resolved diagnosis has been shown to improve specificity of peanut allergy diagnosis by differentiating between dominant and cross-reactive allergens, its long-term prognostic value has never been examined. This study determined whether early component-resolved diagnosis at time of peanut allergy diagnosis in infants and toddlers would provide information in addition to standard specific IgE levels to better predict future evolution of the disease.

A wellcharacterized cohort of peanut allergic subject from a previous study, in which 110 subjects had serum drawn at diagnosis (median age, 14 months) was evaluated over a period of time for for IgE to peanut recombinant Ara h 2 and Ara h 8, Ara h 9 and plant cross-reactive carbohydrate MUXF3 (CCD); 94 for Ara h 1; and 91 for Ara h 3 and recombinant Pru p 4.

Both prevalence and levels of Ara h 8-, Ara h 9-, CCD-, and Pru p4-specific IgE were low in the cohort at diagnosis. In contrast, specific IgE against Ara h 1, Ara h 2, and Ara h 3 was detected in 63%, 95%, and 43% of patients, respectively.

Levels of Ara h 1-, Ara h2-, and Ara h 3-specific IgE correlated with the persistance of peanut allergy. Peanut IgE diversity defined by the sum of IgE detectable tests to the three dominant allergens also correlated strongly with remission. However, when analyzed with a log regression multivariate analysis including peanut-IgE levels, those association did not reach significance.

Long-term prognostic value of component-resolved diagnosis in infants and toddlers with peanut allergy.  
Begin P, Vitte J, Paradis L, Paradis J, Bongrand P, Chanez P, Des RA.
Pediatr Allergy Immunol 2014 Mar 18;

Index

Allergen-, Food allergy-, Intolerance-related articles

Rapid specific IgE assay (ImmunoCAP(R) RAPID) and skin prick test in the diagnosis of allergic disease. [Japanese]  
Komiyama K, Masumoto A, Nishihara F, Kobayashi T, Soma T, Hagiwara K, Kanazawa M, Nagata M.
Arerugi 2013 Dec;62(12):1631-1641
Click to view abstract

Total IgE, mosquito saliva specific IgE and CD4+ count in HIV-infected patients with and without pruritic papular eruptions.  
Jiamton S, Kaewarpai T, Ekapo P, Kulthanan K, Hunnangkul S, Boitano JJ, Wongkamchai S.
Asian Pac J Allergy Immunol 2014 Mar;32(1):53-59
Click to view abstract

A preliminary study of the acaricidal activity of clove oil, Eugenia caryophyllus.  
Mahakittikun V, Soonthornchareonnon N, Foongladda S, Boitano JJ, Wangapai T, Ninsanit P.
Asian Pac J Allergy Immunol 2014 Mar;32(1):46-52
Click to view abstract

Identification and characterization of a pan-allergen profilin, a major allergen from Caryota mitis pollen.  
Liu X, Xiao X, Xia L, Yang PC, Liu Z, Li L.
Asian Pac J Allergy Immunol 2014 Mar;32(1):39-45
Click to view abstract

Prevention of food allergy in the real life.  
Tham EH, Rajakulendran M, Shek LP.
Asian Pac J Allergy Immunol 2014 Mar;32(1):16-24
Click to view abstract

Peanut allergens: an overview.  
Saiz J, Montealegre C, Marina ML, Garcia-Ruiz C.
Crit Rev Food Sci Nutr 2013;53(7):722-737

Response to 'Health risks of genetically modified foods'.  
Rickard C.
Crit Rev Food Sci Nutr 2010 Jan;50(1):85-91

The Key Events Dose-Response Framework: a foundation for examining variability in elicitation thresholds for food allergens.  
Taylor SL, Gendel SM, Houben GF, Julien E.
Crit Rev Food Sci Nutr 2009 Sep;49(8):729-739

Unusual shift from IgE-mediated milk allergy to food protein-induced enterocolitis syndrome.  
Banzato C, Piacentini GL, Comberiati P, Mazzei F, Boner AL, Peroni DG.
Eur Ann Allergy Clin Immunol 2013 Dec;45(6):209-211
Click to view abstract

Predictive value ofMP4 (Milk Prick Four), a panel of skin prick test for the diagnosis of pediatric immediate cow's milk allergy.  
Onesimo R, Monaco S, Greco M, Caffarelli C, Calvani M, Tripodi S, Sopo SM.
Eur Ann Allergy Clin Immunol 2013 Dec;45(6):201-208
Click to view abstract

Contact urticaria to Cannabis sativa due to a lipid transfer protein (LTP).  
Rojas Perez-Ezquerra P, Sanchez-Morillas L, vila-Ferandez G, Ruiz-Hornillos FJ, Carrasco G, Herranz MM, Laguna Martinez JJ, Bartolome B.
Allergol Immunopathol (Madr ) 2014 Mar 20;

Successful oral tolerance induction to cow's milk in a child with allergy to extensively hydrolysed formula.  
Santos N, Gaspar A, Borrego LM, Morais-Almeida M.
Allergol Immunopathol (Madr ) 2014 Mar 20;

Establishing a cut-off for the serum levels of specific IgE to milk and its components for cow's milk allergy: Results from a specific population.  
Castro AP, Pastorino AC, Gushken AK, Kokron CM, Filho UD, Jacob CM.
Allergol Immunopathol (Madr ) 2014 Jan 29;

Are skin prick tests really safe? A case of anaphylaxis caused by skin prick testing with inhalant allergens.  
Babayigit HA, Cipe F, Aydogmus C.
Allergol Immunopathol (Madr ) 2014 Jan 29;

Legumes steam allergy in childhood: Update of the reported cases.  
Vitaliti G, Pavone P, Spataro G, Giunta L, Guglielmo F, Falsaperla R.
Allergol Immunopathol (Madr ) 2014 Jan 7;

Profilin sensitisation in a Mediterranean population.  
Huertas AJ, Carreno A, Merida C, Pajaron-Fernandez MJ, Ramirez-Hernandez M, Carnes J.
Allergol Immunopathol (Madr ) 2014 Jan 7;

Challenge test to bisphosphonates in patients with hypersensitivity reactions to drugs.  
Minciullo PL, Allegra A, D'Angelo A, Musolino C, Gangemi S.
Allergol Immunopathol (Madr ) 2014 Jan 7;

Prevalence of parent-reported immediate hypersensitivity food allergy in Chilean school-aged children.  
Hoyos-Bachiloglu R, Ivanovic-Zuvic D, Alvarez J, Linn K, Thone N, de Los Angeles PM, Borzutzky A.
Allergol Immunopathol (Madr ) 2014 Jan 2;

Pomegranate anaphylaxis due to cross-reactivity with Peach LTP (Pru p 3).  
Almeida EM, Bartolome B, Faria EG, Sousa NG, Luis AS.
Allergol Immunopathol (Madr ) 2013 Nov 22;

Drug allergy in tertiary care in Turkey: Results of a national survey. The ADAPT study: Adult drug allergy perception in Turkey.  
Celik GE, Karakaya G, Ozturk AB, Gelincik A, Abadoglu O, Sin A, Damadoglu E, Yilmaz I, Demirturk M, Dursun B, Ozdemir SK, Celikel S, Degirmenci P, Bozkurt B, Goksel O, Erkekol FO, Aydin O, Kav.
Allergol Immunopathol (Madr ) 2013 Oct 23;

Perioperative allergic reactions: Experience in a Flemish referral centre.  
Antunes J, Kochuyt AM, Ceuppens JL.
Allergol Immunopathol (Madr ) 2013 Oct 23;

Perioperative anaphylactic reactions: Review and procedure protocol in paediatrics.  
Michavila Gomez AV, Belver Gonzalez MT, Alvarez NC, Giner Munoz MT, Hernando S, Porto Arceo JA, Indurain BV.
Allergol Immunopathol (Madr ) 2013 Nov 11;

Coconut anaphylaxis: Case report and review.  
Michavila GA, Amat BM, Gonzalez Cortes MV, Segura NL, Moreno Palanques MA, Bartolome B.
Allergol Immunopathol (Madr ) 2013 Nov 11;

Epidemiology of food allergy in Latin America.  
Sanchez J, Sanchez A.
Allergol Immunopathol (Madr ) 2013 Oct 24;

Allergy to quince.  
Antolín-Amérigo D, Barbarroja-Escudero J, Sánchez-González MJ, Rodríguez-Rodríguez M, Pineda F, Alvarez-Mon M.
Allergol Immunopathol (Madr ) 2013 Oct 28;

Relationship between skin prick and atopic patch test reactivity to aeroallergens and disease severity in children with atopic dermatitis.  
Kutlu A, Karabacak E, Aydin E, Ozturk S, Taskapan O, Aydinoz S, Bozkurt B.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):369-373

Fixed drug eruption due to etoricoxibe - A case report.  
Antunes J, Prates S, Leiria-Pinto P.
Allergol Immunopathol (Madr ) 2013 Aug 21;

Double-blind food challenges in children in general paediatric practice: Useful and safe, but not without pitfalls.  
Oole-Groen CJ, Brand PL.
Allergol Immunopathol (Madr ) 2013 Aug 21;

Unexpected cross-reactivity in a cat-allergy patient. An allergic reaction at the circus.  
Feleszko W, Zalewski BM, Kulus M.
Allergol Immunopathol (Madr ) 2013 Aug 21;

Laboratorial characteristics of patients with diarrhoea suffering from egg white allergy.  
Liu F, Lin LR, Zhang HL, Liu GL, Tong ML, Zeng YL, Huang SJ, Huang CL, Liu LL, Yang TC.
Allergol Immunopathol (Madr ) 2013 Jul 11;

Latex-specific IgE and its recombinant fractions in a child with cerebrospinal eosinophilia.  
Sa AB, Mallozi MC, Zanon N, Sole D.
Allergol Immunopathol (Madr ) 2013 Jul 6;

IgE-mediated reaction induced by arugula (Eruca sativa) ingestion compared with a spectrum of Brassicaceae proteins.  
Damiani E, Aloia AM, Priore MG, Pastore A, Lovecchio A, Errico M, Ferrannini A, Macchia L.
Allergol Immunopathol (Madr ) 2013 Jul 4;

Effect of different diets on Tyrophagus putrescentiae population and amelioration of their immunological disorder by garlic.  
Abdel-Salam BK.
Allergol Immunopathol (Madr ) 2013 Jul 2;

Position document: IgE-mediated allergy to egg protein.  
Martorell A, Alonso E, Bone J, Echeverria L, Lopez MC, Martin F, Nevot S, Plaza AM.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):320-336

Rosmarinus officinalis L. as cause of contact dermatitis.  
Miroddi M, Calapai G, Isola S, Minciullo PL, Gangemi S.
Allergol Immunopathol (Madr ) 2013 Jul 1;

Practical interest of both skin prick test and specific IgE in the evaluation of tolerance acquisition in IgE mediated cow's milk allergy (CMA). A clinical retrospective study in a cohort of 184 children.  
Payot F, Berthiller J, Kassai B, Brunet AS, Villard-Truc F, Lachaux A.
Allergol Immunopathol (Madr ) 2013 Jun 19;

Adverse reaction after administration of progesterone.  
Calapai G, Imbesi S, Miroddi M, Isola S, Venuto L, Navarra M, Gangemi S.
Allergol Immunopathol (Madr ) 2013 Jun 1;

Heat immersion therapy-A new approach for contact dermatitis to propolis?  
Munstedt K.
Allergol Immunopathol (Madr ) 2013 May 29;

Influence of iodinated contrast media on the activities of histamine inactivating enzymes diamine oxidase and histamine N-methyltransferase in vitro.  
Kuefner MA, Feurle J, Petersen J, Uder M, Schwelberger HG.
Allergol Immunopathol (Madr ) 2013 Apr 8;

Confirmed penicillin allergy among patients receiving benzathine penicillin prophylaxis for acute rheumatic fever.  
Kaya A, Erkocoglu M, Senkon OG, Ekici FK, Toyran M, Cetin II, Kocabas CN.
Allergol Immunopathol (Madr ) 2013 Apr 8;

Drug allergy in haematopoietic stem cell transplantation.  
Gordon J, Damstetter E, Nardone B, Mehta J, West DP, Cotliar J.
Allergol Immunopathol (Madr ) 2013 Mar 25;

Anaphylactic reaction to bell pepper (Capsicum annuum) in a patient with a latex-fruit syndrome.  
Garcia-Menaya JM, Cordobes-Duran C, Bobadilla-Gonzalez P, Ledesma A, Perez-Rangel I, Sanchez-Vega S, Zambonino MA, Corrales-Vargas S.
Allergol Immunopathol (Madr ) 2013 Mar 25;

Evaluation of the level of house dust mite allergens, Der p 1 and Der f 1 in Iranian homes, a nationwide study.  
Fereidouni M, Fereidouni F, Hadian M, Nourani HS, Mazandarani M, Ziaee M.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):381-386

Expression of grape class IV chitinase in Spodoptera frugiperda (Sf9) insect cells.  
Falak R, Varasteh AR, Ketabdar H, Sankian M.
Allergol Immunopathol (Madr ) 2013 Mar 4;

Utility of opium seed extract tests in preventing hypersensitivity reactions during surgery.  
Armentia A, Pineda F, Palacios R, Martin-Gil FJ, Miguel AS, Arenal JJ, Tejedor J, Tef BM.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):56-63

Allergy to all mammalian Bovidae proteins but cow's milk in a child.  
Mori F, Restani P, Pucci N, Ballabio C, Uberti F, Penas E, Novembre E.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):349-350

Occupational airborne contact dermatitis caused by usnic acid in a domestic worker.  
Pacheco D, Travassos AR, Antunes J, Soares de AL, Filipe P, Correia T.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):80-82

Allergic contact dermatitis due to sensitisation to sunscreen in two infants.  
Macias E, Gonzalez AM, De Lamas C, Ponce V, Munoz-Bellido F, Moreno E.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):419-420

Diagnostic usefulness of component-resolved diagnosis by skin prick tests and specific IgE to single allergen components in children with allergy to fruits and vegetables.  
Vieira T, Cunha L, Neves E, Falcao H.
Allergol Immunopathol (Madr ) 2012 Dec 21;

Anaphylaxis to levofloxacin.  
Dewachter P, Mouton-Faivre C.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):418-419

Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.  
Nakonechna A, Dore P, Dixon T, Khan S, Deacock S, Holding S, Abuzakouk M.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):44-49

Diagnostic and therapeutic approaches in respiratory allergy are different depending on the profile of aeroallergen sensitisation.  
Dominguez-Ortega J, Quirce S, Delgado J, Davila I, Marti-Guadano E, Valero A.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):11-18

Serum IgE discriminates allergy from sensitisation better than skin testing.  
Alesina R, De AM, Ciprandi G.
Allergol Immunopathol (Madr ) 2012 Dec 18;

Hypersensitivity pneumonitis caused by metalworking fluid.  
Sastre J, Mur P, Garcia del PM, Aguado E.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):354-355

Food-dependent exercise-induced anaphylaxis (FDEIA) by nectarine in a paediatric patient with weakly positive nectarine prick-by-prick and negative specific IgE to Pru p 3.  
Miceli SS, Monaco S, Giorgio V, Calvani M, Mistrello G, Onesimo R.
Allergol Immunopathol (Madr ) 2013 May;41(3):201-203

Allergy to goat and sheep cheese with tolerance to cow's milk and its derivatives.  
Vinas M, Carnes J, Lopez-Matas MA, Hernandez N, Castillo MJ, Ibero M.
Allergol Immunopathol (Madr ) 2012 Dec 17;

Diagnostic accuracy of atopy patch tests for food allergy in children with atopic dermatitis aged less than two years.  
Yang H, Xiao YZ, Luo XY, Tan Q, Wang H.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):22-28

Asthma and paracetamol: could we really know what happens between them?  
Moral L, Marco N, Fuentes MJ, Toral T, Cano R, Pena MA.
Allergol Immunopathol (Madr ) 2013 Jul;41(4):261-264

Risk of adverse IgE-mediate reaction at the first egg ingestion in children with atopic dermatitis. Results of a case-control study.  
Miceli SS, Monaco S, Giorgio V, Calvani M, Tripodi S, Onesimo R.
Allergol Immunopathol (Madr ) 2012 Dec 17;

Mite hypersensitivity in patients with rhinitis and rhinosinusitis living in a tropical environment.  
Sanchez-Borges M, Fernandez-Caldas E, Capriles-Hulett A, Caballero-Fonseca F.
Allergol Immunopathol (Madr ) 2012 Dec 17;

Food allergen selective thermal processing regimens may change oral tolerance in infancy.  
Kosti RI, Triga M, Tsabouri S, Priftis KN.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):407-417

Cold-induced urticaria with systemic reactions after hymenoptera sting lasting for 10 years.  
Kutlu A, Aydin E, Goker K, Karabacak E, Ozturk S.
Allergol Immunopathol (Madr ) 2013 Jul;41(4):283-284

First annual register of allergenic pollen in Talca, Chile.  
Mardones P, Grau M, Araya J, Cordova A, Pereira I, Penailillo P, Silva R, Moraga A, guilera-Insunza R, Yepes-Nunez JJ, Palomo I.
Allergol Immunopathol (Madr ) 2013 Jul;41(4):233-238

Food protein-induced enterocolitis syndrome (FPIES) and well cooked foods: a working hypothesis.  
Miceli SS, Buonsenso D, Monaco S, Crocco S, Longo G, Calvani M.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):346-348

Milk-induced wheezing in children with asthma.  
Murray MG, Kanuga J, Yee E, Bahna SL.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):310-314

Allergic hypersensitivity to Deflazacort.  
Pacheco D, Travassos AR, Antunes J, Silva R, Lopes A, Marques MS.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):352-354

Polysensitisation to rubber additives and dyes in shoes and clothes.  
Pacheco D, Travassos AR, Antunes J, Silva R, Marques MS.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):350-352

Modulation of IgE immunoreactivity to broad bean proteins after food processing in a Moroccan population.  
Bousfiha A, Aarab L.
Allergol Immunopathol (Madr ) 2014 Jan;42(1):29-34

Hypersensitivity to lansoprazole with tolerance to other proton pump inhibitors: does cross-reactivity between proton pump inhibitors really exist?  
Karabacak E, Kutlu A, Aydin E, Ozturk S.
Allergol Immunopathol (Madr ) 2013 Mar;41(2):136-137

Storage mite sensitisation is associated with early life village residence in Turkey.  
Celebioglu E, Ozturk AB, Comert S, Karakaya G, Kalyoncu AF.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):402-406

Injection site reaction to adalimumab: Positive skin test and successful rapid desensitisation.  
Bavbek S, Ataman S, Bankova L, Castells M.
Allergol Immunopathol (Madr ) 2013 May;41(3):204-206

Common features of anaphylaxis in children.  
Serbes M, Can D, Atlihan F, Gunay I, Asilsoy S, Altinoz S.
Allergol Immunopathol (Madr ) 2013 Jul;41(4):255-260

Fixed drug eruption due to ibuprofen with patch test positive on the residual lesion.  
Sanchez-Morillas L, Rojas Perez-Ezquerra P, Gonzalez Morales ML, Gonzalez-Mendiola R, Laguna Martinez JJ.
Allergol Immunopathol (Madr ) 2013 May;41(3):203-204

Similar prevalence, different spectrum: IgE-mediated food allergy among Turkish adolescents.  
Mustafayev R, Civelek E, Orhan F, Yuksel H, Boz AB, Sekerel BE.
Allergol Immunopathol (Madr ) 2013 Nov;41(6):387-396

Are drug provocation tests still necessary to test the safety of COX-2 inhibitors in patients with cross-reactive NSAID hypersensitivity?  
Celik GE, Erkekol FO, Aydin O, Demirel YS, Misirligil Z.
Allergol Immunopathol (Madr ) 2013 May;41(3):181-188

The safety of codeine in patients with non-steroidal anti-inflammatory drug hypersensitivity: a preliminary study.  
Celebioglu E, Karakaya G, Kalyoncu AF.
Allergol Immunopathol (Madr ) 2013 May;41(3):163-168

Knowledge and attitudes of primary care physicians regarding food allergy and anaphylaxis in Turkey.  
Erkocoglu M, Civelek E, Azkur D, Ozcan C, Ozturk K, Kaya A, Metin A, Kocabas CN.
Allergol Immunopathol (Madr ) 2013 Sep;41(5):292-297

Urticaria pigmentosa in a female patient with celiac disease: response to a gluten-free diet.  
Rodrigo L, Perez-Martinez I, Lucendo AJ.
Allergol Immunopathol (Madr ) 2013 Mar;41(2):128-130

Sodium metabisulphite allergy with multiple food and drug hypersensitivities in a five-year-old child: A case report and literature review.  
Vitaliti G, Guglielmo F, Giunta L, Pavone P, Falsaperla R.
Allergol Immunopathol (Madr ) 2014 Mar 20;

A neglected cause for chronic spontaneous urticaria in children: Helicobacter pylori.  
Akelma AZ, Cizmeci MN, Mete E, Tufan N, Bozkurt B.
Allergol Immunopathol (Madr ) 2014 Mar 20;
Click to view abstract

Epicutaneous Administration of Papain Induces IgE and IgG Responses in a Cysteine Protease Activity-Dependent Manner.  
Iida H, Takai T, Hirasawa Y, Kamijo S, Shimura S, Ochi H, Nishioka I, Maruyama N, Ogawa H, Okumura K, Ikeda S.
Allergol Int 2014 Mar 25;
Click to view abstract

Agreement between the skin prick test and specific serum IgE for egg white and cow's milk allergens in young infant with atopic dermatitis.  
Yang HJ, Park MJ, Youn SY, Yoo S, Min TK, Jeon YH, Lee HW, Lee JS, Pyun BY.
Allergol Int 2014 Mar 25;
Click to view abstract

Is there a need for repetition of skin test in childhood allergic diseases? repetition of skin test and allergic diseases.  
Dogru M, Bostanci I, Ozmen S, Ginis T, Duman H.
Allergol Int 2014 Mar 25;
Click to view abstract

Continuous 6-year follow-up study of sensitization to Japanese cedar pollen and onset in schoolchildren.  
Kanazawa A, Terada T, Ozasa K, Hyo S, Araki N, Kawata R, Takenaka H.
Allergol Int 2014 Mar;63(1):95-101
Click to view abstract

Oral mite anaphylaxis caused by mite-contaminated okonomiyaki/ pancake-mix in Japan: 8 case reports and a review of 28 reported cases.  
Takahashi K, Taniguchi M, Fukutomi Y, Sekiya K, Watai K, Mitsui C, Tanimoto H, Oshikata C, Tsuburai T, Tsurikisawa N, Minoguchi K, Nakajima H, Akiyama K.
Allergol Int 2014 Mar;63(1):51-56
Click to view abstract

Allergic bronchopulmonary aspergillosis mimicking relapsing chronic eosinophilic pneumonia in non-asthma patient.  
Lee JY, Choi H, Chon GR.
Allergol Int 2014 Mar;63(1):133-135

Geographical variation in the prevalence of sensitization to common aeroallergens in adults: the GA LEN survey.  
Newson RB, van RR, Forsberg B, Janson C, Lotvall J, Dahlen SE, Toskala EM, Baelum J, Brozek GM, Kasper L, Kowalski ML, Howarth PH, Fokkens WJ, Bachert C, Keil T, Kramer U, Bislimovska J, Gjoma.
Allergy 2014 Mar 21;
Click to view abstract

A case of serum sickness-like reaction and anaphylaxis - induced simultaneously by rifampin.  
Kim DH, Choi YH, Kim HS, Yu JE, Koh YI.
Allergy Asthma Immunol Res 2014 Mar;6(2):183-185
Click to view abstract

Cross-reactivity to Acetaminophen and Celecoxib According to the Type of Nonsteroidal Anti-inflammatory Drug Hypersensitivity.  
Kim YJ, Lim KH, Kim MY, Jo EJ, Lee SY, Lee SE, Yang MS, Song WJ, Kang HR, Park HW, Chang YS, Cho SH, Min KU, Kim SH.
Allergy Asthma Immunol Res 2014 Mar;6(2):156-162
Click to view abstract

Prevalence of immediate-type food allergy in early childhood in Seoul.  
Park M, Kim D, Ahn K, Kim J, Han Y.
Allergy Asthma Immunol Res 2014 Mar;6(2):131-136
Click to view abstract

Usefulness of nBos d 4, 5 and nBos d 8 specific IgE antibodies in cow's milk allergic children.  
Cingolani A, Di PS, Cerasa M, Rapino D, Consilvio NP, Attanasi M, Scaparrotta A, Marcovecchio ML, Mohn A, Chiarelli F.
Allergy Asthma Immunol Res 2014 Mar;6(2):121-125
Click to view abstract

The usefulness of component-resolved diagnostics in food allergy.  
Ahn K.
Allergy Asthma Immunol Res 2014 Mar;6(2):103-104

BSACI Guideline for the Diagnosis and Management of Cow's Milk Allergy.  
Luyt D, Ball H, Makwana N, Green MR, Bravin K, Nasser SM, Clark AT.
Clin Exp Allergy 2014 Mar 3;
Click to view abstract

Allergy to illicit drugs and narcotics.  
Swerts S, Van GA, Leysen J, Faber M, Sabato V, Bridts CH, Jorens PG, De Clerck LS, Ebo DG.
Clin Exp Allergy 2014 Mar;44(3):307-318
Click to view abstract

Glucoamylase is a major allergen of Schizophyllum commune.  
Toyotome T, Satoh M, Yahiro M, Watanabe A, Nomura F, Kamei K.
Clin Exp Allergy 2014 Mar;44(3):450-457

The fraction of exhaled nitric oxide improves prediction of clinical allergic reaction to peanut challenge in children.  
Preece K, Bhatia R, Belcher J, Patchett K, McElduff P, Collison A, Mattes J.
Clin Exp Allergy 2014 Mar;44(3):371-380
Click to view abstract

Markers of gut mucosal inflammation and cow's milk specific immunoglobulins in non-IgE cow's milk allergy.  
Merras-Salmio L, Kolho KL, Pelkonen AS, Kuitunen M, Makela MJ, Savilahti E.
Clin Transl Allergy 2014;4(1):8
Click to view abstract

Prevalence and characteristics of food allergy in urban minority adults.  
Agarwal S, Wang J.
Ann Allergy Asthma Immunol 2014 Mar 18;

On the cover-green ash.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Mar;112(3):A13

Radiocontrast-induced iodide sialadenopathy and neutrophilic dermatosis.  
Fok JS, Ramachandran T, Berce M, Smith WB.
Ann Allergy Asthma Immunol 2014 Mar;112(3):267-268

Long-term follow-up of IgE-mediated food allergy: determining persistence versus clinical tolerance.  
Burks AW, Land MH.
Ann Allergy Asthma Immunol 2014 Mar;112(3):200-206

Mouse and cockroach exposure in rural Arkansas Delta region homes.  
Coleman AT, Rettiganti M, Bai S, Brown RH, Perry TT.
Ann Allergy Asthma Immunol 2014 Mar;112(3):256-260
Click to view abstract

Impermeable dust mite covers in the primary and tertiary prevention of allergic disease: a meta-analysis.  
Arroyave WD, Rabito FA, Carlson JC, Friedman EE, Stinebaugh SJ.
Ann Allergy Asthma Immunol 2014 Mar;112(3):237-248
Click to view abstract

Low-dose gamma irradiation of food protein increases its allergenicity in a chronic oral challenge.  
Vaz AF, Souza MP, Medeiros PL, Melo AM, Silva-Lucca RA, Santana LA, Oliva ML, Perez KR, Cuccovia IM, Correia MT.
Food Chem Toxicol 2013 Jan;5146-52

Assessment of possible allergenicity of hypothetical ORFs in common food crops using current bioinformatic guidelines and its implications for the safety assessment of GM crops.  
Young GJ, Zhang S, Mirsky HP, Cressman RF, Cong B, Ladics GS, Zhong CX.
Food Chem Toxicol 2012 Oct;50(10):3741-3751

Effect of thermal processing and gamma-irradiation on allergenicity of legume proteins.  
Kasera R, Singh AB, Kumar R, Lavasa S, Prasad KN, Arora N.
Food Chem Toxicol 2012 Oct;50(10):3456-3461

Impact of thermal processing and the Maillard reaction on the basophil activation of hazelnut allergic patients.  
Cucu T, De MB, Bridts C, Devreese B, Ebo D.
Food Chem Toxicol 2012 May;50(5):1722-1728

Evaluation of IgE reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy.  
Grozdanovic M, Popovic M, Polovic N, Burazer L, Vuckovic O, tanaskovic-Markovic M, Lindner B, Petersen A, Gavrovic-Jankulovic M.
Food Chem Toxicol 2012 Mar;50(3-4):1013-1018

Gallium poisoning: a rare case report.  
Ivanoff CS, Ivanoff AE, Hottel TL.
Food Chem Toxicol 2012 Feb;50(2):212-215

Fragrance material review on 3-phenylpropyl cinnamate.  
Bhatia SP, Cocchiara J, Wellington GA, Lalko J, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S252-S255

Fragrance material review on 3-phenyl-1-propanol.  
Bhatia SP, Wellington GA, Cocchiara J, Lalko J, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S246-S251

Fragrance material review on 3-phenylpropyl isobutyrate.  
Bhatia SP, Cocchiara J, Wellington GA, Lalko J, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S242-S245

Fragrance material review on ethylene dodecanedioate.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S212-S218

Fragrance material review on omega-6-hexadecenlactone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S207-S211

Fragrance material review on 16-hydroxy-7-hexadecenoic acid lactone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S149-S151

Fragrance material review on hexadecanolide.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S183-S188

Prediction and characterization of the linear IgE epitopes for the major soybean allergen beta-conglycinin using immunoinformatics tools.  
Sun X, Shan X, Yan Z, Zhang Y, Guan L.
Food Chem Toxicol 2013 Jun;56254-260

Estimation of the safe use concentrations of the preservative 1,2-benzisothiazolin-3-one (BIT) in consumer cleaning products and sunscreens.  
Novick RM, Nelson ML, Unice KM, Keenan JJ, Paustenbach DJ.
Food Chem Toxicol 2013 Jun;5660-66

Fragrance material review on omega-pentadecalactone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S193-S201

Mapping IgE binding epitopes of major shrimp (Penaeus monodon) allergen with immunoinformatics tools.  
Zheng LN, Lin H, Pawar R, Li ZX, Li MH.
Food Chem Toxicol 2011 Nov;49(11):2954-2960

Fragrance material review on cyclopentadecanone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S142-S148

Fragrance material review on cyclohexadec-8-en-1-one (mixture of cis and trans isomers).  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S109-S111

Fragrance material review on 3-methylcyclopentadecenone (mixed isomers).  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S85-S92

Fragrance material review on 10-oxahexadecanolide.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S158-S162

Fragrance material review on oxacyclohexadecane-2,13-dione.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S202-S206

Fragrance material review on oxacycloheptadec-10-ene-2-one.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S189-S192

Fragrance material review on 12-oxahexadecanolide.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S168-S173

Fragrance material review on 11-oxahexadecanolide.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S163-S167

Fragrance material review on 4-cyclopentadecen-1-one, (Z)-.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S112-S116

Fragrance material review on 4-cyclopentadecen-1-one.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S117-S119

Fragrance material review on E- and Z-oxacyclohexadec-12(+13)-en-2-one.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S152-S157

Fragrance material review on 3-methyl-1-cyclopentadecanone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S120-S125

Fragrance material review on cyclohexadecanone.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S104-S108

Fragrance material review on cycloheptadeca-9-en-1-one.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S93-S97

Fragrance material review on ethylene brassylate.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S174-S182

Fragrance material review on 5-cyclohexadecen-1-one.  
McGinty D, Letizia CS, Api AM.
Food Chem Toxicol 2011 Dec;49 Suppl 2S98-103

Endogenous allergen upregulation: transgenic vs. traditionally bred crops.  
Herman RA, Ladics GS.
Food Chem Toxicol 2011 Oct;49(10):2667-2669

Effects of oral monosodium glutamate in mouse models of asthma.  
Yoneda J, Chin K, Torii K, Sakai R.
Food Chem Toxicol 2011 Jan;49(1):299-304

Travelling with Anisakis allergens.  
Ubeira FM.
Int Arch Allergy Immunol 2014 Mar 6;163(4):243-244

Penicillin allergy as a public health measure.  
Solensky R.
J Allergy Clin Immunol 2014 Mar;133(3):797-798

Allergen microarray detects high prevalence of asymptomatic IgE sensitizations to tropical pollen-derived carbohydrates.  
Cabauatan CR, Lupinek C, Scheiblhofer S, Weiss R, Focke-Tejkl M, Bhalla PL, Singh MB, Knight PA, van HM, Ramos JD, Valenta R.
J Allergy Clin Immunol 2014 Mar;133(3):910-914

Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5.  
Focke-Tejkl M, Campana R, Reininger R, Lupinek C, Blatt K, Valent P, Pavkov-Keller T, Keller W, Valenta R.
J Allergy Clin Immunol 2014 Mar;133(3):836-845
Click to view abstract

Traffic-related air pollution is associated with airway hyperresponsiveness.  
Kim BJ, Lee SY, Kwon JW, Jung YH, Lee E, Yang SI, Kim HY, Seo JH, Kim HB, Kim HC, Leem JH, Kwon HJ, Hong SJ.
J Allergy Clin Immunol 2014 Mar 15;

Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food.  
Maggadottir SM, Hill DA, Ruymann K, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Chikwava K, Verma R, Liacouras CA, Spergel JM.
J Allergy Clin Immunol 2014 Mar 15;

Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity.  
Mahdavinia M, Carter RG, Ocampo CJ, Stevens W, Kato A, Tan BK, Kern RC, Conley DB, Chandra R, Hulse KE, Suh LA, Norton JE, Peters AT, Grammer LC, Schwartz LB, Schleimer RP.
J Allergy Clin Immunol 2014 Mar 15;

Present state of Japanese cedar pollinosis: The national affliction.  
Yamada T, Saito H, Fujieda S.
J Allergy Clin Immunol 2014 Mar;133(3):632-639
Click to view abstract

Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1,3-galactose.  
Commins SP, James HR, Stevens W, Pochan SL, Land MH, King C, Mozzicato S, Platts-Mills TA.
J Allergy Clin Immunol 2014 Mar 19;
Click to view abstract

An autoclave treatment reduces the solubility and antigenicity of an allergenic protein found in buckwheat flour.  
Tomotake H, Yamazaki R, Yamato M.
J Food Prot 2012 Jun;75(6):1172-1175

Viability and antigenicity of anisakis simplex after conventional and microwave heating at fixed temperatures.  
Vidacek S, De Las HC, Solas MT, Garcia ML, Mendizabal A, Tejada M.
J Food Prot 2011 Dec;74(12):2119-2126

Detection of shrimp-derived components in food by real-time fluorescent PCR.  
Cao J, Yu B, Ma L, Zheng Q, Zhao X, Xu J.
J Food Prot 2011 Oct;74(10):1776-1781

Liquid chromatography and mass spectrometry in food allergen detection.  
Faeste CK, Ronning HT, Christians U, Granum PE.
J Food Prot 2011 Feb;74(2):316-345

Allergen sanitation in the food industry: a systematic industrial scale approach to reduce hazelnut cross-contamination of cookies.  
Roder M, Baltruweit I, Gruyters H, Ibach A, Mucke I, Matissek R, Vieths S, Holzhauser T.
J Food Prot 2010 Sep;73(9):1671-1679

Allergy to goat/sheep’s milk with good tolerance to cow’s milk but not to cow’s milk cheese: Identification of 1-105 peptide from k-casein as the molecular basis of reactivity toward cow’s milk cheese for two patients.  
Beaumesnil M, Denery-Papini S, Drouet M, Gaudin J-C.
Miscellaneous Res in Immunology 2013: DOI: 10.5171/2013.168397
Abstract

Major histocompatibility complex and other allergy-related candidate genes associated with insect bite hypersensitivity in Icelandic horses.  
Klumplerova M, Vychodilova L, Bobrova O, Cvanova M, Futas J, Janova E, Vyskocil M, Vrtkova I, Putnova L, Dusek L, Marti E, Horin P.
Mol Biol Rep 2013 Apr;40(4):3333-3340

Structural biology of mite allergens.  
Cui Y.
Mol Biol Rep 2013 Jan;40(1):681-686

Diagnosis of Chenopodium album allergy with a cocktail of recombinant allergens as a tool for component-resolved diagnosis.  
Nouri HR, Sankian M, Vahedi F, Afsharzadeh D, Rouzbeh L, Moghadam M, Varasteh A.
Mol Biol Rep 2012 Mar;39(3):3169-3178

Specific conformational epitope features of pathogenesis-related proteins mediating cross-reactivity between pollen and food allergens.  
Jimenez-Lopez JC, Gachomo EW, Ariyo OA, Baba-Moussa L, Kotchoni SO.
Mol Biol Rep 2012 Jan;39(1):123-130

Molecular cloning, expression, sequence analyses of dust mite allergen Der f 6 and its IgE-binding reactivity with mite allergic asthma patients in southeast China.  
Cui Y, Zhou Y, Shi W, Ma G, Yang L, Wang Y, Li L.
Mol Biol Rep 2012 Feb;39(2):961-968

Long-term prognostic value of component-resolved diagnosis in infants and toddlers with peanut allergy.  
Begin P, Vitte J, Paradis L, Paradis J, Bongrand P, Chanez P, Des RA.
Pediatr Allergy Immunol 2014 Mar 18;

Is the determination of specific IgE against components using ISAC 112 a reproducible technique?  
Martínez-Aranguren R, Lizaso MT, Goikoetxea MJ, García BE, Cabrera-Freitag P, Trellez O3, Sanz ML.
PLoS Med
Click to view abstract Click to view abstract

An assessment of the skin sensitisation hazard of a group of polyfunctional silicones using a weight of evidence approach.  
Petry T, Bosch A, Coste X, Dupuis V, Eigler D, Germain P.
Regul Toxicol Pharmacol 2012 Nov;64(2):305-314

Application of scientific criteria to food allergens of public health importance.  
Chung YJ, Ronsmans S, Crevel RW, Houben GF, Rona RJ, Ward R, Baka A.
Regul Toxicol Pharmacol 2012 Nov;64(2):315-323

Optimised testing strategies for skin sensitization--the LLNA and beyond.  
Basketter D, Crozier J, Hubesch B, Manou I, Mehling A, Scheel J.
Regul Toxicol Pharmacol 2012 Oct;64(1):9-16

Decision trees for evaluating skin and respiratory sensitizing potential of chemicals in accordance with European regulations.  
Selgrade MK, Sullivan KS, Boyles RR, Dederick E, Serex TL, Loveless SE.
Regul Toxicol Pharmacol 2012 Aug;63(3):371-380

Comparison of international food allergen labeling regulations.  
Gendel SM.
Regul Toxicol Pharmacol 2012 Jul;63(2):279-285

Potential allergenicity research of Cry1C protein from genetically modified rice.  
Cao S, He X, Xu W, Luo Y, Ran W, Liang L, Dai Y, Huang K.
Regul Toxicol Pharmacol 2012 Jul;63(2):181-187

Assessing the potency of respiratory allergens: uncertainties and challenges.  
Basketter DA, Kimber I.
Regul Toxicol Pharmacol 2011 Dec;61(3):365-372

Heat stability, its measurement, and its lack of utility in the assessment of the potential allergenicity of novel proteins.  
Privalle L, Bannon G, Herman R, Ladics G, McClain S, Stagg N, Ward J, Herouet-Guicheney C.
Regul Toxicol Pharmacol 2011 Dec;61(3):292-295

Investigation of endogenous soybean food allergens by using a 2-dimensional gel electrophoresis approach.  
Rouquie D, Capt A, Eby WH, Sekar V, Herouet-Guicheney C.
Regul Toxicol Pharmacol 2010 Dec;58(3 Suppl):S47-S53

Evaluation of scientific criteria for identifying allergenic foods of public health importance.  
van Bilsen JH, Ronsmans S, Crevel RW, Rona RJ, Przyrembel H, Penninks AH, Contor L, Houben GF.
Regul Toxicol Pharmacol 2011 Aug;60(3):281-289

Proteomic approaches for qualitative and quantitative characterisation of food allergens.  
Sancho AI, Mills EN.
Regul Toxicol Pharmacol 2010 Dec;58(3 Suppl):S42-S46

Food allergy: stakeholder perspectives on acceptable risk.  
Madsen CB, Crevel R, Chan CH, Dubois AE, DunnGalvin A, Flokstra-de Blok BM, Gowland MH, Hattersley S, Hourihane JO, Norhede P, Pfaff S, Rowe G, Schnadt S, Vlieg-Boerstra BJ.
Regul Toxicol Pharmacol 2010 Jul;57(2-3):256-265

Confirmation of a predicted lack of IgE binding to Cry3Bb1 from genetically modified (GM) crops.  
Nakajima O, Koyano S, Akiyama H, Sawada J, Teshima R.
Regul Toxicol Pharmacol 2010 Apr;56(3):306-311

Comparative study of GH-transgenic and non-transgenic amago salmon (Oncorhynchus masou ishikawae) allergenicity and proteomic analysis of amago salmon allergens.  
Nakamura R, Satoh R, Nakajima Y, Kawasaki N, Yamaguchi T, Sawada J, Nagoya H, Teshima R.
Regul Toxicol Pharmacol 2009 Dec;55(3):300-308

Comments on serious anaphylaxis caused by nine Chinese herbal injections used to treat common colds and upper respiratory tract infections.  
Ji K, Chen J, Li M, Liu Z, Xia L, Wang C, Zhan Z, Wu X.
Regul Toxicol Pharmacol 2009 Nov;55(2):134-138

Acceptable risk of contact allergy in the general population assessed by CE-DUR--a method to detect and categorize contact allergy epidemics based on patient data.  
Thyssen JP, Menne T, Schnuch A, Uter W, White I, White JM, Johansen JD.
Regul Toxicol Pharmacol 2009 Jul;54(2):183-187

Utility of animal models for predicting human allergenicity.  
Lehrer SB, McClain S.
Regul Toxicol Pharmacol 2009 Aug;54(3 Suppl):S46-S51

Murine models for evaluating the allergenicity of novel proteins and foods.  
Aldemir H, Bars R, Herouet-Guicheney C.
Regul Toxicol Pharmacol 2009 Aug;54(3 Suppl):S52-S57

Allergen databases and allergen semantics.  
Gendel SM.
Regul Toxicol Pharmacol 2009 Aug;54(3 Suppl):S7-10

Identifying food proteins with allergenic potential: evolution of approaches to safety assessment and research to provide additional tools.  
Ladics GS, Selgrade MK.
Regul Toxicol Pharmacol 2009 Aug;54(3 Suppl):S2-S6

Utility of rodent models for evaluating protein allergenicity.  
Bowman CC, Selgrade MK.
Regul Toxicol Pharmacol 2009 Aug;54(3 Suppl):S58-S61

Influence of protein expression system on elicitation of IgE antibody responses: experience with lactoferrin.  
Almond RJ, Flanagan BF, Kimber I, Dearman RJ.
Toxicology 2012 Nov 15;301(1-3):50-57

The respiratory allergen glutaraldehyde in the local lymph node assay: sensitization by skin exposure, but not by inhalation.  
van Triel JJ, van Bree BW, Roberts DW, Muijser H, Duistermaat E, Woutersen RA, Kuper CF.
Toxicology 2011 Jan 11;279(1-3):115-122

Food allergy--science and policy needs--The UK Food Standards Agency Research Programme.  
Buck J, Hattersley S, Kimber I.
Toxicology 2010 Dec 30;278(3):319-325

Assessing the risk of type 1 allergy to enzymes present in laundry and cleaning products: evidence from the clinical data.  
Sarlo K, Kirchner DB, Troyano E, Smith LA, Carr GJ, Rodriguez C.
Toxicology 2010 May 27;271(3):87-93


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