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Bird-egg syndrome is one example of the close connection of type I allergies involving inhalant and food allergens. The
sensitization to airborn allergens was proved to preceed the
allergy to ingestive allergens in several studies. Hypersensitivity reactions to bird (feathers, serum, droppings
and meat) and egg yolk allergens are more frequently
observed in bird fanciers (budgerigar, canary, parrot etc.). The pathomechanism of IgE-mediated bird-egg syndrome is
different from pigeon fancier's lung (a form of extrinsic
allergic alveolitis), which is not a subject of the present data
collection. There are some differences in prevalences and
symptoms between bird-egg syndrome and food allergy to egg without sensitization to bird allergens. For example
respiratory reactions are frequent in bird-egg syndrome, while
they are rarely seen in patients with egg allergy only. The
present data collection summarizes information about
prevalence, symptoms, and allergen sources in tabular form.
Molecular biological and allergenic properties of the major
egg yolk allergens alpha-livetin (chicken serum albumin),
apovitellenin I and VI are presented. Up to now only little is
known about the identity of feather allergens. Apart from bird allergens feather mites participate in the cross-sensitization to house dust mite.
Añibarro Bausela B, Besler M, Rancé F, Szépfalusi Z
Internet Symposium on Food Allergens Germany |
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