Overview of Expert Care for Asthma: Annotated Bibliography.
		100%	This review was performed to provide physicians, managed care organisations, and patients with direct access to the diverse research literature bearing on the value of specialist (expert) care for asthma. This report consists of a brief summary of the current status of knowledge, accompanied by an annotated bibliography which documents and expands on the narrative summary. Includes Epidemiology and economics of asthma, Expert care for asthma, Allergen control for asthma, Immunotherapy for asthma, and Practice parameters and quality of care for asthma. Allergy, Asthma & Immunology Online   USA
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			Rice (Oryza sativa)
		0%	Rice is the main and most important food taken every day in Eastern Asia. Frequency of IgE-mediated rice allergy is about 10 % in atopic subjects in Japan. Prevalences are much lower in Europe and the USA, where rice is mostly recognized as a cereal- associated allergen source. Furthermore rice allergy is more prominent in adults than in children. Details are reviewed in tabular form. Aspects considered are: Prevalence data, symptoms, diagnostic features, sensitivities to major allergens, their molecular biological properties, cross- reactivities and stability to enzymatic and heat treatments. A multigene family of 14-16 kDa proteins presents the major allergens from rice seeds/grain which show significant homology to the alpha- amylase / trypsin inhibitor family from wheat and barley. Other rice seed/grain allergens are a recently described 33-kDa major and a 60-kDa minor allergen. Many efforts, for instance with protease, alkali or hyperpressure treatment, have been made to produce hypoallergenic rice. Several products proved to be effective for the diet of rice allergic individuals with atopic dermatitis. In addition to ingestive allergens rice presents an important aero- allergen (Ory s 1) belonging to the grass pollen group I allergens. Internet Symposium on Food Allergens   Germany
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			Structure and Function Can Determine Important Features in Allergenicity - Mini-Review
		0%	Investigations on the Group I Allergens of the Grasses The structure of an allergen plays a crucial role in type I allergy. It is involved in the sensitization process as well as in allergic reactions that are caused by repetitive exposure. Here, we focused on the abundant group I allergens of grass pollen, which are known for their IgE inducing potential. We identified at least four independent IgE-binding regions (conformational epitopes) on the molecule. A few continuous epitopes were determined, but they seem to be of minor relevance. Matthias Besler Internet Symposium on Food Allergens   Germany
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			The Latex-Fruit Syndrome: A Review on Clinical Features
		0%	During the last decade, latex IgE-mediated allergy has been recognized as a very important medical problem. At the same time, many studies have dealt with allergic cross-reactions between aeroallergens and foods. Recently, a "latex-fruit syndrome" has been postulated, because there is clear evidence of the existence of a significant clinical association between allergies to latex and certain fruits. Several studies have demonstrated that from 20% to 60% of latex-allergic patients show IgE-mediated reactions to a wide variety of foods, mainly fruits. Although implicated foods vary among the studies, banana, avocado, chestnut and kiwi are the most frequently involved. Clinical manifestations of these reactions may vary from oral allergy syndrome to severe anaphylactic reactions, which are not uncommon, thus demonstrating the clinical relevance of this syndrome. The diagnosis of food hypersensitivities associated with latex allergy is based on the clinical history of immediate adverse reactions, suggestive of an IgE-mediated sensitivity. Prick by prick test with the fresh foods implicated in the reactions shows an 80% concordance with the clinical diagnosis, and therefore it seems to be the best diagnostic test currently available in order to confirm the suspicion of latex-fruit allergy. Once the diagnosis is achieved, a diet free of the offending fruits is mandatory. Recently, some of the common allergens responsible for the cross-reactions among latex and the fruits most commonly implicated in the syndrome have been identified. Class I chitinases, with an N-terminal hevein like domain, which cross-react with the major latex allergen "hevein", seem to be the panallergens responsible for the latex-fruit syndrome. Carlos BLANCO Internet Symposium on Food Allergens   Germany
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			The Major Allergen from Hen's Egg White: Ovomucoid (Gal d 1)
		0%	Ovomucoid (OM) is the dominant allergen from hen's egg white. Frequency of sensitization to OM varies from 34-97% in egg allergic patients. The carbohydrate moieties of OM present up to 22-29%. It consists of 186 amino acids forming three tandem domains, each providing trypsin inhibitory activity. Effective isolation and purification of OM was attained by combined IEC / SEC and by automated fraction collection using capillary zone electrophoresis. Matrix-assisted laser desorption / ionisation time of flight (MALDI-TOF) mass spectrometry revealed an average Mr of 28.0 kDa. Immunoblot and RAST inhibition experiments of native and deglycosylated OM indicate that only peptide epitopes participate in IgE- binding structures of OM. All 3 domains exhibit IgE- binding potencies. At least 8 independent IgE binding regions using synthetic peptides of OM were identified. T-cell proliferative response in PBMC from egg allergic patients could be induced by all 3 domains, predominantly by the second and third domains. Internet Symposium on Food Allergens   Germany
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			The Use of In Vitro Tests for IgE Antibody - Position Statement
		30%	Physician Reference Materials: Position Statements on the Use of In Vitro Tests for IgE Antibody in the Specific Diagnosis of IgE-Mediated Disorders and in the Formulation of Allergen Immunotherapy AAAAI American Academy of Allergy, Asthma and Immunology   USA
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