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Allergens
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Professional Organisation's Site Excellent A Checklist Of Allergens

71%
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Article about allergies of all kinds, includes a checklist

Healingwell.com   USA

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Commercial Organisation's Site Good A Patient's Asthma Primer

68%
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A document outlining the following key points: Asthma words you should know, how the lungs work, what is asthma, is your asthma under control, triggers of asthma, irritants of asthma, allergens: environmental control, occupational asthma, medications that worsen asthma, asthma medications, relievers, preventers, warning signs of poor asthma control, questions and answers.

Canadian Asthma Consensus Guidelines   Canada

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Commercial Organisation's Site Moderate About Common Allergens

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A reasonable article on Airborne Allergens, House Dust, Mould and Animal Dander

Allergy Clean Environments   USA

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Professional Organisation's Site Excellent All About Allergies

67%
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Dust, cats, peanuts, cockroaches. An odd grouping, but one with a common thread: allergies. If your child has allergies, he is not alone. Up to 50 million Americans, including two million children, have some type of allergy.

KidsHealth.org   USA

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Commercial Organisation's Site Good All About Allergy

50%
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What is allergy?
What are allergic reactions?
What causes allergic reactions?
Who is affected by allergy?
How is allergy diagnosed?
How is allergy treated?

ViaHealth   USA

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Commercial Organisation's Site Excellent Allergen Avoidance

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You may be able to improve your allergy by making some changes at home. Making just a few changes could improve
your symptoms considerably, even though it will probably not stop your allergy completely.

BBC Online   United Kingdom

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For Health Professionals Commercial Organisation's Site Excellent Allergen Components (of the TRUE Patch Test)

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Nickel sulfate
p-tert-Butylphenol formaldehyde resin
Wool alcohols
Epoxy resin
Neomycin sulfate
Carba mix
Potassium dichromate
Black rubber mix
Caine mix
Cl+Me- Isothiazolinone
Fragrance mix
Quaternium-15
Colophony
Mercaptobenzothiazole
Paraben mix
p-Phenylenediamine
Negative control
Formaldehyde
Balsam of Peru
Mercapto mix
Ethylenediamine dihydrochloride
Thimerosal
Cobalt dichloride
Thiuram mix

T.R.U.E. Test - Allergen Patch Test   USA

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For Health Professionals Professional Organisation's Site Excellent Allergen Data Collection: Apple (Malus domestica)

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The data collection summarizes the results of an extensive literature search in tabular form. Detailed information about prevalence, symptoms, and allergen sources is represented.

While the prevalence of apple allergy in food allergic patients is generally below 2 %, apple allergy is most frequently associated with birch pollinosis in Northern Europe and North America. 40 to 90 % of birch pollen allergic patients are sensitized to this fruit.

Apple is known as one of the major foods involved in so-called "Oral Allergy Syndrome", which presents IgE-mediated symptoms occurring mainly at the mucosa of lips, tongue and throat after ingestion of apples and other fruits. Systemic reactions including anaphylaxis occur more often in apple allergic patients without related pollinosis. The present data collection reviews detailed information on prevalence and symptoms of apple allergy as well as cross-reactivities, molecular biological and allergenic properties of the major apple allergens, and allergenic potencies of different varieties and ripening stages of apples in tabular
form. The allergens are unstable to conventional processing of the fruits like canning, pulping or heating, therefore adverse reactions occur almost exclusively after ingestion of fresh fruits. Due to the labile nature of apple allergens the diagnostic accuracy is highly dependent on the quality of extracts used in testing procedures. Cross-reactive inhalant allergens are tree pollen (predominantly birch) and to a lesser degree mugwort and grass pollen. The major pollen-associated apple allergen is the Bet v 1 homolog protein Mal d 1. Besides Mal d 1, a 31-kDa allergen was highly prevalent in patients with associated tree pollen allergy. Proteins with Mr about 34 kDa and 60 kDa and a profilin homolog allergen are proven to be cross-reactive to pollens. The major allergen in a patient population without pollinosis is the lipid-transfer protein Mal d 3, which is suggested to be cross-reactive to homolog proteins in peach and pear.

Matthias Besler

Internet Symposium on Food Allergens   Germany

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For Health Professionals Professional Organisation's Site Excellent Allergen Data Collection: Celery (Apium graveolens)

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IgE mediated reactions to celery are common in food allergic adults in Europe. Sensitization to celery is frequently associated with birch and/or mugwort pollinosis, hence the term "birch-mugwort- celery- syndrome" has been established. There is evidence that birch pollen and celery allergy are highly related in Central Europe, while celery allergy is most frequently related to mugwort pollen in Southern Europe. Moreover, allergies to carrot and spices, predominantly of the umbelliferous family, are highly associated to celery allergy. Celery can induce allergic reactions of immediate type from oral contact urticaria to anaphylactic shock.

About 30% of patients with oral allergy syndrome are allergic to celery. Diagnostic tests like skin tests with raw celery and active allergen extracts have high positive predictive values, while the negative predictive values are low. Roots, also called tuber or celeriac, and sticks from the celery plant are used in nutrition and diagnostic procedures.

Usually the frequency of sensitization to celery tuber is higher than to celery stick in celery allergic subjects. Celery tuber and stick are consumed as a raw or cooked vegetable and as a spice which is a common hidden allergen in various processed foods. Despite its high allergenic potency and at least partial thermostability celery and celery products are currently not included in mandatory labelling regulations for food allergens. At least three groups of cross- reactive allergens have been identified in celery: 1. Bet v 1 homologous 16 kDa allergen (Api g 1) with IgE cross- reactivity to birch pollen, fruits, and vegetables (eg. apple and carrot), 2. The actin- binding panallergen profilin (Api g 4) with appr. 15 kDa, and 3. Allergens in the range of 30-70 kDa, including the recently described 55/58 kDa isoallergens (Api g 5) cross-reactive to birch pollen and mugwort pollen.

The present data collection reviews detailed information on the prevalence and symptoms of celery allergy as well as cross- reactivities, and molecular biological and allergenic properties of the major celery allergens in tabular form.

Ballmer-Weber B, Besler M, Hoffmann-Sommergruber K, Vieths S,

Internet Symposium on Food Allergens   Germany

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For Health Professionals Professional Organisation's Site Excellent Allergen Data Collection: Codfish (Gadus morhua)

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The data collection summarizes the results of an extensive literature search in tabular form. Detailed information about prevalence, symptoms, and allergen sources is represented.

IgE-mediated hypersensitivity to fish is a common problem in fish processing communities. Fish allergy is more frequent in children and young adults of whom about 88 % show IgE-mediated reactions to codfish. The codfish inhabits the North, Baltic and White Sea, and the Northern Atlantic and Pacific. It is used as a fresh, salted, dried or more recently as a processed food ingredient of e.g. surimi. Although food processing such as cooking and canning could alter the allergenic potency of codfish allergens, one should be aware of the retained significant allergenicity of these products. An overview of prevalence data, symptoms, diagnostic and therapeutic features of codfish allergy as well as molecular biological and allergenic properties of codfish allergens is given in tabular form. The major allergen
from codfish Gad c 1 (Allergen M) belongs to the Ca2+-binding parvalbumins. Despite the high degree of cross-reactivity to other fish species some species may be tolerated by certain allergic individuals.

Matthias Besler

Internet Symposium on Food Allergens   Germany

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